The Association Between Small Airway Obstruction and Emphysema Phenotypes in COPD

Airflow limitation in COPD is due to a variable combination of small airway obstruction and centrilobular emphysema (CLE) and/or panlobular emphysema (PLE), but the relationship between these three different phenotypes is poorly understood. This study compares the severity of small airway obstructio...

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Veröffentlicht in:	Chest 2007-05, Vol.131 (5), p.1372-1378
Hauptverfasser:	Kim, Won-Dong, Ling, Sean H., Coxson, Harvey O., English, John C., Yee, John, Levy, Robert D., Paré, Peter D., Hogg, James C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Airway Obstruction - etiology Airway Obstruction - pathology alpha 1-Antitrypsin Deficiency - complications alpha 1-Antitrypsin Deficiency - pathology Biological and medical sciences Cardiology. Vascular system Case-Control Studies centrilobular emphysema Chronic obstructive pulmonary disease, asthma COPD emphysema Emphysema - complications Emphysema - pathology Errors of metabolism Female FEV1 Forced Expiratory Volume Humans Image Processing, Computer-Assisted Lung - pathology Lung - physiopathology Male Medical sciences Metabolic diseases Middle Aged morphometry panlobular emphysema Phenotype Pneumology Proteins and glycoproteins Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - pathology Severity of Illness Index small airway obstruction small airway wall thickness Spirometry α1-antitrypsin deficiency
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