Twin-to-twin transfusion syndrome: an antiangiogenic state?

Objective An imbalanced chronic blood flow between the donor and recipient twin through placental vascular anastomoses is the accepted pathophysiology of twin-to-twin transfusion syndrome (TTTS). Vascular endothelial growth factor receptor-1 (VEGFR-1) mRNA is overexpressed only in the syncytiotropho...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2008-04, Vol.198 (4), p.382.e1-382.e8
Hauptverfasser:	Kusanovic, Juan Pedro, MD, Romero, Roberto, MD, Espinoza, Jimmy, MD, Nien, Jyh Kae, MD, Kim, Chong Jai, MD, Mittal, Pooja, MD, Edwin, Sam, PhD, Erez, Offer, MD, Gotsch, Francesca, MD, Mazaki-Tovi, Shali, MD, Than, Nandor G., MD, PhD, Soto, Eleazar, MD, Camacho, Natalia, MD, Gomez, Ricardo, MD, Quintero, Ruben, MD, Hassan, Sonia S., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult angiogenesis angiogenic factors Antigens, CD - blood Biological and medical sciences birthweight discordancy Case-Control Studies Endoglin Enzyme-Linked Immunosorbent Assay Female Fetofetal Transfusion - blood Gynecology. Andrology. Obstetrics Humans Medical sciences monochorionic Neovascularization, Physiologic Obstetrics and Gynecology Placenta Growth Factor placental growth factor PlGF Pregnancy Pregnancy Proteins - blood Receptors, Cell Surface - blood sFlt1 sVEGFR-1 TTTS twin pregnancy Vascular Endothelial Growth Factor Receptor-1 - blood
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