Conservative treatment of an early ectopic pregnancy in a cesarean scar with systemic methotrexate--case report
Pregnancy implanted in a cesarean scar is rare, and is a life-threatening condition due to high risk of uterine rupture, hemorrhage, hysterectomy, and maternal mortality. We describe a 26-year-old woman who presented with five weeks of amenorrhea and a serum hCG level of 10,440 mIU/ml. Transvaginal...
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| Veröffentlicht in: | Clinical and experimental obstetrics & gynecology 2008, Vol.35 (1), p.73-75 |
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| container_title | Clinical and experimental obstetrics & gynecology |
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| creator | Iyibozkurt, A C Topuz, S Gungor, F Kalelioglu, I H Cigerli, E Akhan, S E |
| description | Pregnancy implanted in a cesarean scar is rare, and is a life-threatening condition due to high risk of uterine rupture, hemorrhage, hysterectomy, and maternal mortality.
We describe a 26-year-old woman who presented with five weeks of amenorrhea and a serum hCG level of 10,440 mIU/ml. Transvaginal sonography revealed a gestational sac of 15 x 11 mm containing a yolk sac located in a previous cesarean scar. She was successfully treated conservatively with multi-dose methotrexate. No side-effects were encountered. The serum hCG levels were undetectable in 58 days. The patient had normal menstrual cycles afterwards.
In the view of increasing cesarean rates, healthcare professionals should be aware of the possibility of a scar pregnancy and the potentially life threatening sequelae. Early diagnosis by transvaginal sonography can improve outcome and minimize the need for emergent surgery. Conservative treatment with systemic methotrexate is an effective option in selected patients. |
| format | Article |
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We describe a 26-year-old woman who presented with five weeks of amenorrhea and a serum hCG level of 10,440 mIU/ml. Transvaginal sonography revealed a gestational sac of 15 x 11 mm containing a yolk sac located in a previous cesarean scar. She was successfully treated conservatively with multi-dose methotrexate. No side-effects were encountered. The serum hCG levels were undetectable in 58 days. The patient had normal menstrual cycles afterwards.
In the view of increasing cesarean rates, healthcare professionals should be aware of the possibility of a scar pregnancy and the potentially life threatening sequelae. Early diagnosis by transvaginal sonography can improve outcome and minimize the need for emergent surgery. Conservative treatment with systemic methotrexate is an effective option in selected patients.</description><identifier>ISSN: 0390-6663</identifier><identifier>PMID: 18390088</identifier><language>eng</language><publisher>Canada</publisher><subject>Abortifacient Agents, Nonsteroidal - administration & dosage ; Adult ; Cesarean Section ; Endometrium - diagnostic imaging ; Endometrium - pathology ; Female ; Humans ; Injections, Intramuscular ; Methotrexate - administration & dosage ; Pregnancy ; Pregnancy, Abdominal - diagnostic imaging ; Pregnancy, Abdominal - drug therapy ; Ultrasonography</subject><ispartof>Clinical and experimental obstetrics & gynecology, 2008, Vol.35 (1), p.73-75</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18390088$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Iyibozkurt, A C</creatorcontrib><creatorcontrib>Topuz, S</creatorcontrib><creatorcontrib>Gungor, F</creatorcontrib><creatorcontrib>Kalelioglu, I H</creatorcontrib><creatorcontrib>Cigerli, E</creatorcontrib><creatorcontrib>Akhan, S E</creatorcontrib><title>Conservative treatment of an early ectopic pregnancy in a cesarean scar with systemic methotrexate--case report</title><title>Clinical and experimental obstetrics & gynecology</title><addtitle>Clin Exp Obstet Gynecol</addtitle><description>Pregnancy implanted in a cesarean scar is rare, and is a life-threatening condition due to high risk of uterine rupture, hemorrhage, hysterectomy, and maternal mortality.
We describe a 26-year-old woman who presented with five weeks of amenorrhea and a serum hCG level of 10,440 mIU/ml. Transvaginal sonography revealed a gestational sac of 15 x 11 mm containing a yolk sac located in a previous cesarean scar. She was successfully treated conservatively with multi-dose methotrexate. No side-effects were encountered. The serum hCG levels were undetectable in 58 days. The patient had normal menstrual cycles afterwards.
In the view of increasing cesarean rates, healthcare professionals should be aware of the possibility of a scar pregnancy and the potentially life threatening sequelae. Early diagnosis by transvaginal sonography can improve outcome and minimize the need for emergent surgery. Conservative treatment with systemic methotrexate is an effective option in selected patients.</description><subject>Abortifacient Agents, Nonsteroidal - administration & dosage</subject><subject>Adult</subject><subject>Cesarean Section</subject><subject>Endometrium - diagnostic imaging</subject><subject>Endometrium - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>Injections, Intramuscular</subject><subject>Methotrexate - administration & dosage</subject><subject>Pregnancy</subject><subject>Pregnancy, Abdominal - diagnostic imaging</subject><subject>Pregnancy, Abdominal - drug therapy</subject><subject>Ultrasonography</subject><issn>0390-6663</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo10L1OwzAUBWAPIFoKr4DuxBbJiR3HHlHFn1SJBeboxr2hQYkdbKeQtycS7XSG8-kM54KtuTA8U0qJFbuO8YtzKSuVX7FVrpeGa71mfutdpHDE1B0JUiBMA7kEvgV0QBj6GcgmP3YWxkCfDp2doXOAYCni4h1EiwF-unSAOMdEw0IHSge_rP1ioiyzGAkCjT6kG3bZYh_p9pQb9vH0-L59yXZvz6_bh102FtykDEVlpTWNaLUio6iVgmtlci0tkS1LWe5zxQvTGGP2vFGNKqhSRlaFNW2VF2LD7v93x-C_J4qpHrpoqe_RkZ9iXXGpeSnMAu9OcGoG2tdj6AYMc32-SPwBcEBjGw</recordid><startdate>2008</startdate><enddate>2008</enddate><creator>Iyibozkurt, A C</creator><creator>Topuz, S</creator><creator>Gungor, F</creator><creator>Kalelioglu, I H</creator><creator>Cigerli, E</creator><creator>Akhan, S E</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2008</creationdate><title>Conservative treatment of an early ectopic pregnancy in a cesarean scar with systemic methotrexate--case report</title><author>Iyibozkurt, A C ; Topuz, S ; Gungor, F ; Kalelioglu, I H ; Cigerli, E ; Akhan, S E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-a37c4c9b3f86e96ef430869184ceec5545d16029b999d0b6b62e769472c9f7123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Abortifacient Agents, Nonsteroidal - administration & dosage</topic><topic>Adult</topic><topic>Cesarean Section</topic><topic>Endometrium - diagnostic imaging</topic><topic>Endometrium - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>Injections, Intramuscular</topic><topic>Methotrexate - administration & dosage</topic><topic>Pregnancy</topic><topic>Pregnancy, Abdominal - diagnostic imaging</topic><topic>Pregnancy, Abdominal - drug therapy</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Iyibozkurt, A C</creatorcontrib><creatorcontrib>Topuz, S</creatorcontrib><creatorcontrib>Gungor, F</creatorcontrib><creatorcontrib>Kalelioglu, I H</creatorcontrib><creatorcontrib>Cigerli, E</creatorcontrib><creatorcontrib>Akhan, S E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental obstetrics & gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Iyibozkurt, A C</au><au>Topuz, S</au><au>Gungor, F</au><au>Kalelioglu, I H</au><au>Cigerli, E</au><au>Akhan, S E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conservative treatment of an early ectopic pregnancy in a cesarean scar with systemic methotrexate--case report</atitle><jtitle>Clinical and experimental obstetrics & gynecology</jtitle><addtitle>Clin Exp Obstet Gynecol</addtitle><date>2008</date><risdate>2008</risdate><volume>35</volume><issue>1</issue><spage>73</spage><epage>75</epage><pages>73-75</pages><issn>0390-6663</issn><abstract>Pregnancy implanted in a cesarean scar is rare, and is a life-threatening condition due to high risk of uterine rupture, hemorrhage, hysterectomy, and maternal mortality.
We describe a 26-year-old woman who presented with five weeks of amenorrhea and a serum hCG level of 10,440 mIU/ml. Transvaginal sonography revealed a gestational sac of 15 x 11 mm containing a yolk sac located in a previous cesarean scar. She was successfully treated conservatively with multi-dose methotrexate. No side-effects were encountered. The serum hCG levels were undetectable in 58 days. The patient had normal menstrual cycles afterwards.
In the view of increasing cesarean rates, healthcare professionals should be aware of the possibility of a scar pregnancy and the potentially life threatening sequelae. Early diagnosis by transvaginal sonography can improve outcome and minimize the need for emergent surgery. Conservative treatment with systemic methotrexate is an effective option in selected patients.</abstract><cop>Canada</cop><pmid>18390088</pmid><tpages>3</tpages></addata></record> |
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| ispartof | Clinical and experimental obstetrics & gynecology, 2008, Vol.35 (1), p.73-75 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Abortifacient Agents, Nonsteroidal - administration & dosage Adult Cesarean Section Endometrium - diagnostic imaging Endometrium - pathology Female Humans Injections, Intramuscular Methotrexate - administration & dosage Pregnancy Pregnancy, Abdominal - diagnostic imaging Pregnancy, Abdominal - drug therapy Ultrasonography |
| title | Conservative treatment of an early ectopic pregnancy in a cesarean scar with systemic methotrexate--case report |
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