Synthesis and glycogen phosphorylase inhibitor activity of 2,3-dihydrobenzo[1,4]dioxin derivatives

Novel 5-benzyl and 5-benzylidene-thiazolidine-2,4-diones carrying 2,3-dihydrobenzo[1,4]dioxin pharmacophore were synthesized and their glycogen phosphorylase inhibitor activity was also studied.

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Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry 2007-06, Vol.15 (12), p.4048-4056
Hauptverfasser:	Juhász, László, Docsa, Tibor, Brunyászki, Attila, Gergely, Pál, Antus, Sándor
Format:	Artikel
Sprache:	eng
Schlagworte:	2,3-Dihydrobenzo[1,4]dioxin Biological and medical sciences Diabetes Dioxins - chemical synthesis Dioxins - pharmacology Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - pharmacology General and cellular metabolism. Vitamins Glitazones Glycogen Phosphorylase - antagonists & inhibitors Glyogen phosphorylase Magnetic Resonance Spectroscopy Mass Spectrometry Medical sciences Pharmacology. Drug treatments
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