ATP7B Copper-Regulated Traffic and Association With the Tight Junctions: Copper Excretion Into the Bile

Background & Aims: The copper transporter ATP7B plays a central role in the elimination of excess copper by the liver into the bile, yet the site of its action remains controversial. The studies reported here examine the correspondence between the site of ATP7B action and distribution and the pa...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2008-04, Vol.134 (4), p.1215-1223
Hauptverfasser:	Hernandez, Sonia, Tsuchiya, Yo, García–Ruiz, Josefa P, Lalioti, Vassiliki, Nielsen, Søren, Cassio, Doris, Sandoval, Ignacio V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - immunology Adenosine Triphosphatases - metabolism Animals Antibodies, Neoplasm - analysis Bile - metabolism Blotting, Western Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Cation Transport Proteins - immunology Cation Transport Proteins - metabolism Cell Line, Tumor Copper - metabolism Copper-transporting ATPases Electrophoresis, Polyacrylamide Gel Gastroenterology and Hepatology Hepatocytes - metabolism Hepatocytes - pathology Humans Liver - metabolism Liver - pathology Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Neoplasms, Experimental - metabolism Liver Neoplasms, Experimental - pathology Male Microscopy, Fluorescence Rats Rats, Wistar
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