Plasmid-mediated quinolone resistance determinants qnr and aac(6′)-Ib-cr in extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in China

Objectives To characterize the prevalence of plasmid-mediated quinolone resistance determinants qnr and aac(6′)-Ib-cr in extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae. Methods qnrA, qnrB, qnrS, aac(6′)-Ib-cr and ESBL-encoding genes were detected by PCR. MI...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2008-05, Vol.61 (5), p.1003-1006
Hauptverfasser:	Jiang, Yan, Zhou, Zhihui, Qian, Ying, Wei, Zeqing, Yu, Yunsong, Hu, Songnian, Li, Lanjuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Proteins - genetics Biological and medical sciences China - epidemiology conjugation Drug Resistance, Multiple, Bacterial - genetics Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli Infections - epidemiology Escherichia coli Infections - microbiology Escherichia coli Proteins - genetics Genes, Bacterial - genetics Genotype Humans Klebsiella Infections - epidemiology Klebsiella Infections - microbiology Klebsiella pneumoniae - enzymology Klebsiella pneumoniae - genetics Medical sciences PFGE Pharmacology. Drug treatments Plasmids - genetics Quinolones - pharmacology Southern hybridization
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