Protection against Escherichia coli infection by antibody to the Staphylococcus aureus poly-N-acetylglucosamine surface polysaccharide

Poly-N-acetylglucosamine (PNAG) is a surface polysaccharide produced by Staphylococcus aureus and Staphyloccus epidermidis and is an effective target for opsonic and protective Ab for these two organisms. Recently, it has been found that Escherichia coli produces an exo-polysaccharide, designated po...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-05, Vol.104 (18), p.7528-7533
Hauptverfasser:	Cerca, Nuno, Maira-Litrán, Tomás, Jefferson, Kimberly K, Grout, Martha, Goldmann, Donald A, Pier, Gerald B
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylglucosamine - immunology Animals Antibodies Antibodies, Bacterial - immunology Antigens Antiserum Bacteria Biological Sciences Disease Models, Animal Escherichia coli Escherichia coli - immunology Escherichia coli - isolation & purification Escherichia coli Infections - immunology Escherichia coli Infections - pathology Escherichia coli Infections - prevention & control Genetic loci Infections Mice Polysaccharides Polysaccharides, Bacterial - immunology Staphylococcus Staphylococcus aureus Staphylococcus aureus - immunology Urinary tract infections Vaccination
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