Histologic subtypes of oral squamous cell carcinoma: prognostic relevance

Squamous cell carcinoma (SCC) is the most prevalent malignant neoplasm of the oral cavity. The conventional tumour and several histologic subtypes of SCC present morphologic features and specific behaviour when they occur in the oral mucosa. For example, basaloid SCC is an aggressive tumour and verr...

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Veröffentlicht in:Journal (Canadian Dental Association) 2007-05, Vol.73 (4), p.339-344
Hauptverfasser: Pereira, Michele Conceição, Oliveira, Denise Tostes, Landman, Gilles, Kowalski, Luiz Paulo
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creator Pereira, Michele Conceição
Oliveira, Denise Tostes
Landman, Gilles
Kowalski, Luiz Paulo
description Squamous cell carcinoma (SCC) is the most prevalent malignant neoplasm of the oral cavity. The conventional tumour and several histologic subtypes of SCC present morphologic features and specific behaviour when they occur in the oral mucosa. For example, basaloid SCC is an aggressive tumour and verrucous carcinoma has the lowest invasive and metastatic potential; however, the clinical and biologic course of these oral SCC variants has not been completely established. Furthermore, although numerous clinical and histologic features associated with oral SCC have been identified, none shows unequivocal prognostic significance. The purpose of this article is to review the various subtypes of oral SCC, emphasizing problems in their histologic diagnosis and prognosis.
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subjects Cancer
Carcinoma, Basosquamous - pathology
Carcinoma, Squamous Cell - classification
Carcinoma, Squamous Cell - pathology
Carcinoma, Verrucous - pathology
Dentistry
Humans
Maxillofacial surgery
Medical diagnosis
Medical prognosis
Mouth Neoplasms - classification
Mouth Neoplasms - pathology
Prognosis
title Histologic subtypes of oral squamous cell carcinoma: prognostic relevance
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