Calcifying pseudoneoplasm of the spine
Abstract Calcifying pseudoneoplasms have been rarely reported to involve the spine. Diagnostically, MRI characteristics have not been well-described. We present the case of a 59-year-old woman with a C8 radiculopathy and history significant for metastatic breast cancer. MRI showed a C7-T1 extradural...
Gespeichert in:
| Veröffentlicht in: | Clinical neurology and neurosurgery 2008-04, Vol.110 (4), p.392-395 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 395 |
|---|---|
| container_issue | 4 |
| container_start_page | 392 |
| container_title | Clinical neurology and neurosurgery |
| container_volume | 110 |
| creator | Park, Paul Schmidt, Lindsay A Shah, Gaurang V Tran, Nghi K Gandhi, Dheeraj Marca, Frank La |
| description | Abstract Calcifying pseudoneoplasms have been rarely reported to involve the spine. Diagnostically, MRI characteristics have not been well-described. We present the case of a 59-year-old woman with a C8 radiculopathy and history significant for metastatic breast cancer. MRI showed a C7-T1 extradural mass with an isointense signal to the spinal cord on T1- and T2-weighted sequences. Mild peripheral enhancement was also noted. The patient underwent a laminectomy to accomplish resection of the underlying lesion. The mass was firm, tan-colored, and adherent to the adjacent dura. A gross total resection was achieved and, postoperatively, the patient had resolution of her radiculopathy. Pathologic analysis confirmed a calcifying pseudoneoplasm. Calcifying pseudoneoplasms can cause exclusively axial pain or may induce radicular or myelopathic symptoms. The pathogenesis is unclear, although the lesions are usually benign. MRI findings can vary, but typically the lesions are extradural, well-demarcated, and mildly enhance peripherally. Surgical resection, either subtotal or total, is highly successful. |
| doi_str_mv | 10.1016/j.clineuro.2007.12.006 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70472326</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0303846707003587</els_id><sourcerecordid>2732955531</sourcerecordid><originalsourceid>FETCH-LOGICAL-c479t-6c3e9777b2f23ac626d0f207f2f8a6d984964391c9d14cb7a3c5fad9c920cc9e3</originalsourceid><addsrcrecordid>eNqFkU9v1DAUxC0EokvhK1QrIXpLsJ8T_7kgqhUUpEocgLPlfXkGL9kk2Buk_fY42qWVeuHky2_mjWcYuxK8Flyot7sa-zjQnMYaONe1gJpz9YSthNFQKavMU7biksvKNEpfsBc57zjnUirznF0IAw0YgBW73vgeYzjG4cd6yjR340Dj1Pu8X49hffhJ6zyVOy_Zs-D7TK_O7yX7_vHDt82n6u7L7efNzV2FjbaHSqEkq7XeQgDpUYHqeACuAwTjVWdNY1UjrUDbiQa32ktsg-8sWuCIluQluz75Tmn8PVM-uH3MSH3vS6w5O80bDRJUAV8_AnfjnIaSzQkuwTa6BVEodaIwjTknCm5Kce_TsUBu6dHt3L8e3dKjE-BKj0V4dbaft3vqHmTn4grw5gz4jL4PyQ8Y8z0HHFpjdVu49yeOSmt_IiWXMdKA1MVEeHDdGP-f5d0jiwWL5eovOlJ--LfLReC-Lqsvo3Nd9m6Nln8BbdSnUQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1032947521</pqid></control><display><type>article</type><title>Calcifying pseudoneoplasm of the spine</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>ProQuest Central UK/Ireland</source><creator>Park, Paul ; Schmidt, Lindsay A ; Shah, Gaurang V ; Tran, Nghi K ; Gandhi, Dheeraj ; Marca, Frank La</creator><creatorcontrib>Park, Paul ; Schmidt, Lindsay A ; Shah, Gaurang V ; Tran, Nghi K ; Gandhi, Dheeraj ; Marca, Frank La</creatorcontrib><description>Abstract Calcifying pseudoneoplasms have been rarely reported to involve the spine. Diagnostically, MRI characteristics have not been well-described. We present the case of a 59-year-old woman with a C8 radiculopathy and history significant for metastatic breast cancer. MRI showed a C7-T1 extradural mass with an isointense signal to the spinal cord on T1- and T2-weighted sequences. Mild peripheral enhancement was also noted. The patient underwent a laminectomy to accomplish resection of the underlying lesion. The mass was firm, tan-colored, and adherent to the adjacent dura. A gross total resection was achieved and, postoperatively, the patient had resolution of her radiculopathy. Pathologic analysis confirmed a calcifying pseudoneoplasm. Calcifying pseudoneoplasms can cause exclusively axial pain or may induce radicular or myelopathic symptoms. The pathogenesis is unclear, although the lesions are usually benign. MRI findings can vary, but typically the lesions are extradural, well-demarcated, and mildly enhance peripherally. Surgical resection, either subtotal or total, is highly successful.</description><identifier>ISSN: 0303-8467</identifier><identifier>EISSN: 1872-6968</identifier><identifier>DOI: 10.1016/j.clineuro.2007.12.006</identifier><identifier>PMID: 18242822</identifier><identifier>CODEN: CNNSBV</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Biological and medical sciences ; Breast cancer ; Calcifying pseudoneoplasm ; Calcinosis - diagnosis ; Calcinosis - pathology ; Calcinosis - surgery ; Cervical Vertebrae - pathology ; Cervical Vertebrae - surgery ; Diagnosis, Differential ; Epidural Neoplasms - diagnosis ; Epidural Neoplasms - pathology ; Epidural Neoplasms - surgery ; Female ; Humans ; Laminectomy ; Magnetic Resonance Imaging ; Medical research ; Medical sciences ; Middle Aged ; Neurology ; Neurosurgery ; Pain ; Radiculopathy ; Radiculopathy - etiology ; Spinal cord ; Spine ; Surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Thoracic Vertebrae - pathology ; Thoracic Vertebrae - surgery</subject><ispartof>Clinical neurology and neurosurgery, 2008-04, Vol.110 (4), p.392-395</ispartof><rights>Elsevier B.V.</rights><rights>2007 Elsevier B.V.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c479t-6c3e9777b2f23ac626d0f207f2f8a6d984964391c9d14cb7a3c5fad9c920cc9e3</citedby><cites>FETCH-LOGICAL-c479t-6c3e9777b2f23ac626d0f207f2f8a6d984964391c9d14cb7a3c5fad9c920cc9e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1032947521?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,782,786,3554,27933,27934,46004,64394,64396,64398,72478</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20258975$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18242822$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, Paul</creatorcontrib><creatorcontrib>Schmidt, Lindsay A</creatorcontrib><creatorcontrib>Shah, Gaurang V</creatorcontrib><creatorcontrib>Tran, Nghi K</creatorcontrib><creatorcontrib>Gandhi, Dheeraj</creatorcontrib><creatorcontrib>Marca, Frank La</creatorcontrib><title>Calcifying pseudoneoplasm of the spine</title><title>Clinical neurology and neurosurgery</title><addtitle>Clin Neurol Neurosurg</addtitle><description>Abstract Calcifying pseudoneoplasms have been rarely reported to involve the spine. Diagnostically, MRI characteristics have not been well-described. We present the case of a 59-year-old woman with a C8 radiculopathy and history significant for metastatic breast cancer. MRI showed a C7-T1 extradural mass with an isointense signal to the spinal cord on T1- and T2-weighted sequences. Mild peripheral enhancement was also noted. The patient underwent a laminectomy to accomplish resection of the underlying lesion. The mass was firm, tan-colored, and adherent to the adjacent dura. A gross total resection was achieved and, postoperatively, the patient had resolution of her radiculopathy. Pathologic analysis confirmed a calcifying pseudoneoplasm. Calcifying pseudoneoplasms can cause exclusively axial pain or may induce radicular or myelopathic symptoms. The pathogenesis is unclear, although the lesions are usually benign. MRI findings can vary, but typically the lesions are extradural, well-demarcated, and mildly enhance peripherally. Surgical resection, either subtotal or total, is highly successful.</description><subject>Biological and medical sciences</subject><subject>Breast cancer</subject><subject>Calcifying pseudoneoplasm</subject><subject>Calcinosis - diagnosis</subject><subject>Calcinosis - pathology</subject><subject>Calcinosis - surgery</subject><subject>Cervical Vertebrae - pathology</subject><subject>Cervical Vertebrae - surgery</subject><subject>Diagnosis, Differential</subject><subject>Epidural Neoplasms - diagnosis</subject><subject>Epidural Neoplasms - pathology</subject><subject>Epidural Neoplasms - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Laminectomy</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Pain</subject><subject>Radiculopathy</subject><subject>Radiculopathy - etiology</subject><subject>Spinal cord</subject><subject>Spine</subject><subject>Surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Thoracic Vertebrae - pathology</subject><subject>Thoracic Vertebrae - surgery</subject><issn>0303-8467</issn><issn>1872-6968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU9v1DAUxC0EokvhK1QrIXpLsJ8T_7kgqhUUpEocgLPlfXkGL9kk2Buk_fY42qWVeuHky2_mjWcYuxK8Flyot7sa-zjQnMYaONe1gJpz9YSthNFQKavMU7biksvKNEpfsBc57zjnUirznF0IAw0YgBW73vgeYzjG4cd6yjR340Dj1Pu8X49hffhJ6zyVOy_Zs-D7TK_O7yX7_vHDt82n6u7L7efNzV2FjbaHSqEkq7XeQgDpUYHqeACuAwTjVWdNY1UjrUDbiQa32ktsg-8sWuCIluQluz75Tmn8PVM-uH3MSH3vS6w5O80bDRJUAV8_AnfjnIaSzQkuwTa6BVEodaIwjTknCm5Kce_TsUBu6dHt3L8e3dKjE-BKj0V4dbaft3vqHmTn4grw5gz4jL4PyQ8Y8z0HHFpjdVu49yeOSmt_IiWXMdKA1MVEeHDdGP-f5d0jiwWL5eovOlJ--LfLReC-Lqsvo3Nd9m6Nln8BbdSnUQ</recordid><startdate>20080401</startdate><enddate>20080401</enddate><creator>Park, Paul</creator><creator>Schmidt, Lindsay A</creator><creator>Shah, Gaurang V</creator><creator>Tran, Nghi K</creator><creator>Gandhi, Dheeraj</creator><creator>Marca, Frank La</creator><general>Elsevier B.V</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20080401</creationdate><title>Calcifying pseudoneoplasm of the spine</title><author>Park, Paul ; Schmidt, Lindsay A ; Shah, Gaurang V ; Tran, Nghi K ; Gandhi, Dheeraj ; Marca, Frank La</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c479t-6c3e9777b2f23ac626d0f207f2f8a6d984964391c9d14cb7a3c5fad9c920cc9e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Biological and medical sciences</topic><topic>Breast cancer</topic><topic>Calcifying pseudoneoplasm</topic><topic>Calcinosis - diagnosis</topic><topic>Calcinosis - pathology</topic><topic>Calcinosis - surgery</topic><topic>Cervical Vertebrae - pathology</topic><topic>Cervical Vertebrae - surgery</topic><topic>Diagnosis, Differential</topic><topic>Epidural Neoplasms - diagnosis</topic><topic>Epidural Neoplasms - pathology</topic><topic>Epidural Neoplasms - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Laminectomy</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>Pain</topic><topic>Radiculopathy</topic><topic>Radiculopathy - etiology</topic><topic>Spinal cord</topic><topic>Spine</topic><topic>Surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Thoracic Vertebrae - pathology</topic><topic>Thoracic Vertebrae - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Paul</creatorcontrib><creatorcontrib>Schmidt, Lindsay A</creatorcontrib><creatorcontrib>Shah, Gaurang V</creatorcontrib><creatorcontrib>Tran, Nghi K</creatorcontrib><creatorcontrib>Gandhi, Dheeraj</creatorcontrib><creatorcontrib>Marca, Frank La</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical neurology and neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Paul</au><au>Schmidt, Lindsay A</au><au>Shah, Gaurang V</au><au>Tran, Nghi K</au><au>Gandhi, Dheeraj</au><au>Marca, Frank La</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Calcifying pseudoneoplasm of the spine</atitle><jtitle>Clinical neurology and neurosurgery</jtitle><addtitle>Clin Neurol Neurosurg</addtitle><date>2008-04-01</date><risdate>2008</risdate><volume>110</volume><issue>4</issue><spage>392</spage><epage>395</epage><pages>392-395</pages><issn>0303-8467</issn><eissn>1872-6968</eissn><coden>CNNSBV</coden><abstract>Abstract Calcifying pseudoneoplasms have been rarely reported to involve the spine. Diagnostically, MRI characteristics have not been well-described. We present the case of a 59-year-old woman with a C8 radiculopathy and history significant for metastatic breast cancer. MRI showed a C7-T1 extradural mass with an isointense signal to the spinal cord on T1- and T2-weighted sequences. Mild peripheral enhancement was also noted. The patient underwent a laminectomy to accomplish resection of the underlying lesion. The mass was firm, tan-colored, and adherent to the adjacent dura. A gross total resection was achieved and, postoperatively, the patient had resolution of her radiculopathy. Pathologic analysis confirmed a calcifying pseudoneoplasm. Calcifying pseudoneoplasms can cause exclusively axial pain or may induce radicular or myelopathic symptoms. The pathogenesis is unclear, although the lesions are usually benign. MRI findings can vary, but typically the lesions are extradural, well-demarcated, and mildly enhance peripherally. Surgical resection, either subtotal or total, is highly successful.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>18242822</pmid><doi>10.1016/j.clineuro.2007.12.006</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0303-8467 |
| ispartof | Clinical neurology and neurosurgery, 2008-04, Vol.110 (4), p.392-395 |
| issn | 0303-8467 1872-6968 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70472326 |
| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | Biological and medical sciences Breast cancer Calcifying pseudoneoplasm Calcinosis - diagnosis Calcinosis - pathology Calcinosis - surgery Cervical Vertebrae - pathology Cervical Vertebrae - surgery Diagnosis, Differential Epidural Neoplasms - diagnosis Epidural Neoplasms - pathology Epidural Neoplasms - surgery Female Humans Laminectomy Magnetic Resonance Imaging Medical research Medical sciences Middle Aged Neurology Neurosurgery Pain Radiculopathy Radiculopathy - etiology Spinal cord Spine Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Thoracic Vertebrae - pathology Thoracic Vertebrae - surgery |
| title | Calcifying pseudoneoplasm of the spine |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-02T02%3A21%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Calcifying%20pseudoneoplasm%20of%20the%20spine&rft.jtitle=Clinical%20neurology%20and%20neurosurgery&rft.au=Park,%20Paul&rft.date=2008-04-01&rft.volume=110&rft.issue=4&rft.spage=392&rft.epage=395&rft.pages=392-395&rft.issn=0303-8467&rft.eissn=1872-6968&rft.coden=CNNSBV&rft_id=info:doi/10.1016/j.clineuro.2007.12.006&rft_dat=%3Cproquest_cross%3E2732955531%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1032947521&rft_id=info:pmid/18242822&rft_els_id=1_s2_0_S0303846707003587&rfr_iscdi=true |