Radiofrequency ablation and chemoembolization for hepatocellular carcinoma

To provide an up-to-date review of the technique, efficacy, safety and clinical applications for radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). A thorough review of the literature was performed as related to RFA and TACE for the treatment...

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Veröffentlicht in:The cancer journal (Sudbury, Mass.) Mass.), 2008-03, Vol.14 (2), p.117-122
Hauptverfasser: Georgiades, Christos S, Hong, Kelvin, Geschwind, Jean-Francois
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Sprache:eng
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Zusammenfassung:To provide an up-to-date review of the technique, efficacy, safety and clinical applications for radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). A thorough review of the literature was performed as related to RFA and TACE for the treatment of HCC. We mixed these findings with our own extensive research and clinical experience on this subject by drawing from a pool of more than 1000 patients treated with both modalities. TACE has been shown with the work of Llovet, Camma, and Lo to provide a significant survival benefit for patients with unresectable HCC. The former showed a 1-, 2-, and 3-year survival at 57%, 31%, and 26% in the treatment group vs. 32%, 11%, and 3% in the supportive treatment alone group, respectively. Repeatedly, RFA has been shown to be very effective in the treatment of small (
ISSN:1528-9117
1540-336X
DOI:10.1097/ppo.0b013e31816a0fac