Cell growth and detachment from protein-coated PNIPAAm-based copolymers

The cultivation of cells requires the use of unfavorable proteolytic enzymes, which cause cell‐surface modification and also need considerable optimization. Recently, with the development of smart polymers, research has looked to using thermoresponsive polymers as cell culture substrates. These nove...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2007-06, Vol.81A (4), p.870-876
Hauptverfasser:	Moran, Martin T., Carroll, William M., Selezneva, Irina, Gorelov, Alexander, Rochev, Yuri
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Acrylamides - metabolism Acrylic Resins - chemistry Acrylic Resins - metabolism Animals Cell Adhesion Cell Proliferation Collagen - metabolism DNA - metabolism electron microscopy Fibroblasts - cytology Laminin - metabolism Mice Microscopy, Atomic Force Microscopy, Electron, Scanning poly(N-isopropylacrylamide) Polylysine - metabolism Polymers - metabolism protein deposition Proteins - metabolism surface modification Surface Properties thermally responsive material Time Factors
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