Myocardial Delayed Enhancement by Magnetic Resonance Imaging in Patients With Muscular Dystrophy
Myocardial Delayed Enhancement by MRI in Patients With Muscular Dystrophy Marly Conceição Silva, Zilda Maria Alves Meira, Juliana Gurgel Giannetti, Marcelo Moreira da Silva, Alysson Félix Oliveira Campos, Márcia de Melo Barbosa, Geraldo Moll Starling Filho, Rogério de Aguiar Ferreira, Mayana Zatz, C...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2007-05, Vol.49 (18), p.1874-1879 |
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| creator | Silva, Marly Conceição, MD Meira, Zilda Maria Alves, MD, PhD Gurgel Giannetti, Juliana, MD, PhD da Silva, Marcelo Moreira Oliveira Campos, Alysson Félix, RT de Melo Barbosa, Márcia, MD, PhD Filho, Geraldo Moll Starling, MD de Aguiar Ferreira, Rogério, MD Zatz, Mayana, PhD Rochitte, Carlos Eduardo, MD, PhD |
| description | Myocardial Delayed Enhancement by MRI in Patients With Muscular Dystrophy Marly Conceição Silva, Zilda Maria Alves Meira, Juliana Gurgel Giannetti, Marcelo Moreira da Silva, Alysson Félix Oliveira Campos, Márcia de Melo Barbosa, Geraldo Moll Starling Filho, Rogério de Aguiar Ferreira, Mayana Zatz, Carlos Eduardo Rochitte Muscular dystrophy is a genetic disease that involves skeletal and cardiac tissues of humans. We tested whether cardiovascular magnetic resonance can detect myocardial damage in the early stages of muscular dystrophy cardiomyopathy. Ten patients with Duchenne or Becker dystrophies were studied. Myocardial fibrosis was observed in 7 patients, even when left ventricular function was preserved by echocardiography. Patients with myocardial fibrosis had a lower ejection fraction. The lateral wall was most commonly involved, with moderate correlation between segmental fibrosis and dysfunction. Cardiovascular magnetic resonance can identify myocardial fibrosis and may be useful in the early stages of cardiomyopathy in muscular dystrophy. |
| doi_str_mv | 10.1016/j.jacc.2006.10.078 |
| format | Article |
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We tested whether cardiovascular magnetic resonance can detect myocardial damage in the early stages of muscular dystrophy cardiomyopathy. Ten patients with Duchenne or Becker dystrophies were studied. Myocardial fibrosis was observed in 7 patients, even when left ventricular function was preserved by echocardiography. Patients with myocardial fibrosis had a lower ejection fraction. The lateral wall was most commonly involved, with moderate correlation between segmental fibrosis and dysfunction. Cardiovascular magnetic resonance can identify myocardial fibrosis and may be useful in the early stages of cardiomyopathy in muscular dystrophy.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2006.10.078</identifier><identifier>PMID: 17481447</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Agreements ; Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Cardiomyopathies - diagnosis ; Cardiomyopathies - etiology ; Cardiomyopathies - physiopathology ; Cardiovascular ; Child ; Creatine Kinase - blood ; Disease ; Diseases of striated muscles. Neuromuscular diseases ; Fibrosis ; Heart attacks ; Humans ; Image Enhancement ; Internal Medicine ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Muscular dystrophy ; Muscular Dystrophy, Duchenne - complications ; Muscular Dystrophy, Duchenne - physiopathology ; Muscular system ; Myocardium - pathology ; Neurology ; Statistical analysis ; Stroke Volume ; Ultrasonic imaging ; Ventricular Function, Right</subject><ispartof>Journal of the American College of Cardiology, 2007-05, Vol.49 (18), p.1874-1879</ispartof><rights>American College of Cardiology Foundation</rights><rights>2007 American College of Cardiology Foundation</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Elsevier Limited May 8, 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c547t-214af5da56558876ed8dd7f7d7e9cd910770a79a74bc1e6f4cd1957b035ea5b33</citedby><cites>FETCH-LOGICAL-c547t-214af5da56558876ed8dd7f7d7e9cd910770a79a74bc1e6f4cd1957b035ea5b33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S073510970700678X$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18738357$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17481447$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silva, Marly Conceição, MD</creatorcontrib><creatorcontrib>Meira, Zilda Maria Alves, MD, PhD</creatorcontrib><creatorcontrib>Gurgel Giannetti, Juliana, MD, PhD</creatorcontrib><creatorcontrib>da Silva, Marcelo Moreira</creatorcontrib><creatorcontrib>Oliveira Campos, Alysson Félix, RT</creatorcontrib><creatorcontrib>de Melo Barbosa, Márcia, MD, PhD</creatorcontrib><creatorcontrib>Filho, Geraldo Moll Starling, MD</creatorcontrib><creatorcontrib>de Aguiar Ferreira, Rogério, MD</creatorcontrib><creatorcontrib>Zatz, Mayana, PhD</creatorcontrib><creatorcontrib>Rochitte, Carlos Eduardo, MD, PhD</creatorcontrib><title>Myocardial Delayed Enhancement by Magnetic Resonance Imaging in Patients With Muscular Dystrophy</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>Myocardial Delayed Enhancement by MRI in Patients With Muscular Dystrophy Marly Conceição Silva, Zilda Maria Alves Meira, Juliana Gurgel Giannetti, Marcelo Moreira da Silva, Alysson Félix Oliveira Campos, Márcia de Melo Barbosa, Geraldo Moll Starling Filho, Rogério de Aguiar Ferreira, Mayana Zatz, Carlos Eduardo Rochitte Muscular dystrophy is a genetic disease that involves skeletal and cardiac tissues of humans. We tested whether cardiovascular magnetic resonance can detect myocardial damage in the early stages of muscular dystrophy cardiomyopathy. Ten patients with Duchenne or Becker dystrophies were studied. Myocardial fibrosis was observed in 7 patients, even when left ventricular function was preserved by echocardiography. Patients with myocardial fibrosis had a lower ejection fraction. The lateral wall was most commonly involved, with moderate correlation between segmental fibrosis and dysfunction. Cardiovascular magnetic resonance can identify myocardial fibrosis and may be useful in the early stages of cardiomyopathy in muscular dystrophy.</description><subject>Adolescent</subject><subject>Agreements</subject><subject>Biological and medical sciences</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiomyopathies - diagnosis</subject><subject>Cardiomyopathies - etiology</subject><subject>Cardiomyopathies - physiopathology</subject><subject>Cardiovascular</subject><subject>Child</subject><subject>Creatine Kinase - blood</subject><subject>Disease</subject><subject>Diseases of striated muscles. Neuromuscular diseases</subject><subject>Fibrosis</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Image Enhancement</subject><subject>Internal Medicine</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscular dystrophy</subject><subject>Muscular Dystrophy, Duchenne - complications</subject><subject>Muscular Dystrophy, Duchenne - physiopathology</subject><subject>Muscular system</subject><subject>Myocardium - pathology</subject><subject>Neurology</subject><subject>Statistical analysis</subject><subject>Stroke Volume</subject><subject>Ultrasonic imaging</subject><subject>Ventricular Function, Right</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kl2L1DAUhoMo7jj6B7yQgOhdx6RtelKQBdlddWEHxQ_0LqbJ6UxqP8akFfrvTZmBgb3wKnDynJM3D4eQ55xtOOPFm2bTaGM2KWNFLGwYyAdkxYWQSSZKeEhWDDKRcFbCBXkSQsMiKHn5mFxwyCXPc1iRX9t5MNpbp1t6ja2e0dKbfq97gx32I61mutW7Hkdn6BcMQ7_c0NtO71y_o66nn_XoIhjoDzfu6XYKZmq1p9dzGP1w2M9PyaNatwGfnc41-f7-5tvVx-Tu04fbq3d3iRE5jEnKc10Lq0UR80so0EproQYLWBpbcgbANJQa8spwLOrcWF4KqFgmUIsqy9bk9XHuwQ9_Jgyj6lww2La6x2EKClheSFakEXx5D2yGyfcxm-KCFbxM0-htTdIjZfwQgsdaHbzrtJ8VZ2qxrxq12FeL_aUW7cemF6fRU9WhPbecdEfg1QnQwei29tGmC2dOQiYzsXBvjxxGY38dehVMtGzQOo9mVHZw_89xea_dtK538cXfOGM4_1eFVDH1ddmTZU0YxCEgf2b_AEQnt3o</recordid><startdate>20070508</startdate><enddate>20070508</enddate><creator>Silva, Marly Conceição, MD</creator><creator>Meira, Zilda Maria Alves, MD, PhD</creator><creator>Gurgel Giannetti, Juliana, MD, PhD</creator><creator>da Silva, Marcelo Moreira</creator><creator>Oliveira Campos, Alysson Félix, RT</creator><creator>de Melo Barbosa, Márcia, MD, PhD</creator><creator>Filho, Geraldo Moll Starling, MD</creator><creator>de Aguiar Ferreira, Rogério, MD</creator><creator>Zatz, Mayana, PhD</creator><creator>Rochitte, Carlos Eduardo, MD, PhD</creator><general>Elsevier Inc</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20070508</creationdate><title>Myocardial Delayed Enhancement by Magnetic Resonance Imaging in Patients With Muscular Dystrophy</title><author>Silva, Marly Conceição, MD ; Meira, Zilda Maria Alves, MD, PhD ; Gurgel Giannetti, Juliana, MD, PhD ; da Silva, Marcelo Moreira ; Oliveira Campos, Alysson Félix, RT ; de Melo Barbosa, Márcia, MD, PhD ; Filho, Geraldo Moll Starling, MD ; de Aguiar Ferreira, Rogério, MD ; Zatz, Mayana, PhD ; Rochitte, Carlos Eduardo, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c547t-214af5da56558876ed8dd7f7d7e9cd910770a79a74bc1e6f4cd1957b035ea5b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Agreements</topic><topic>Biological and medical sciences</topic><topic>Cardiology</topic><topic>Cardiology. 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Neuromuscular diseases</topic><topic>Fibrosis</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Image Enhancement</topic><topic>Internal Medicine</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscular dystrophy</topic><topic>Muscular Dystrophy, Duchenne - complications</topic><topic>Muscular Dystrophy, Duchenne - physiopathology</topic><topic>Muscular system</topic><topic>Myocardium - pathology</topic><topic>Neurology</topic><topic>Statistical analysis</topic><topic>Stroke Volume</topic><topic>Ultrasonic imaging</topic><topic>Ventricular Function, Right</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silva, Marly Conceição, MD</creatorcontrib><creatorcontrib>Meira, Zilda Maria Alves, MD, PhD</creatorcontrib><creatorcontrib>Gurgel Giannetti, Juliana, MD, PhD</creatorcontrib><creatorcontrib>da Silva, Marcelo Moreira</creatorcontrib><creatorcontrib>Oliveira Campos, Alysson Félix, RT</creatorcontrib><creatorcontrib>de Melo Barbosa, Márcia, MD, PhD</creatorcontrib><creatorcontrib>Filho, Geraldo Moll Starling, MD</creatorcontrib><creatorcontrib>de Aguiar Ferreira, Rogério, MD</creatorcontrib><creatorcontrib>Zatz, Mayana, PhD</creatorcontrib><creatorcontrib>Rochitte, Carlos Eduardo, MD, PhD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silva, Marly Conceição, MD</au><au>Meira, Zilda Maria Alves, MD, PhD</au><au>Gurgel Giannetti, Juliana, MD, PhD</au><au>da Silva, Marcelo Moreira</au><au>Oliveira Campos, Alysson Félix, RT</au><au>de Melo Barbosa, Márcia, MD, PhD</au><au>Filho, Geraldo Moll Starling, MD</au><au>de Aguiar Ferreira, Rogério, MD</au><au>Zatz, Mayana, PhD</au><au>Rochitte, Carlos Eduardo, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Myocardial Delayed Enhancement by Magnetic Resonance Imaging in Patients With Muscular Dystrophy</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2007-05-08</date><risdate>2007</risdate><volume>49</volume><issue>18</issue><spage>1874</spage><epage>1879</epage><pages>1874-1879</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>Myocardial Delayed Enhancement by MRI in Patients With Muscular Dystrophy Marly Conceição Silva, Zilda Maria Alves Meira, Juliana Gurgel Giannetti, Marcelo Moreira da Silva, Alysson Félix Oliveira Campos, Márcia de Melo Barbosa, Geraldo Moll Starling Filho, Rogério de Aguiar Ferreira, Mayana Zatz, Carlos Eduardo Rochitte Muscular dystrophy is a genetic disease that involves skeletal and cardiac tissues of humans. We tested whether cardiovascular magnetic resonance can detect myocardial damage in the early stages of muscular dystrophy cardiomyopathy. Ten patients with Duchenne or Becker dystrophies were studied. Myocardial fibrosis was observed in 7 patients, even when left ventricular function was preserved by echocardiography. Patients with myocardial fibrosis had a lower ejection fraction. The lateral wall was most commonly involved, with moderate correlation between segmental fibrosis and dysfunction. Cardiovascular magnetic resonance can identify myocardial fibrosis and may be useful in the early stages of cardiomyopathy in muscular dystrophy.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17481447</pmid><doi>10.1016/j.jacc.2006.10.078</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Agreements Biological and medical sciences Cardiology Cardiology. Vascular system Cardiomyopathies - diagnosis Cardiomyopathies - etiology Cardiomyopathies - physiopathology Cardiovascular Child Creatine Kinase - blood Disease Diseases of striated muscles. Neuromuscular diseases Fibrosis Heart attacks Humans Image Enhancement Internal Medicine Magnetic Resonance Imaging Male Medical sciences Muscular dystrophy Muscular Dystrophy, Duchenne - complications Muscular Dystrophy, Duchenne - physiopathology Muscular system Myocardium - pathology Neurology Statistical analysis Stroke Volume Ultrasonic imaging Ventricular Function, Right |
| title | Myocardial Delayed Enhancement by Magnetic Resonance Imaging in Patients With Muscular Dystrophy |
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