E-cadherin is a receptor for the common protein pneumococcal surface adhesin A (PsaA) of Streptococcus pneumoniae

Streptococcus pneumoniae (Pnc) binds to nasopharyngeal (NP) epithelial cells in the first steps of nasopharyngeal carriage and colonization through bacterial adhesins. The pneumococcal surface adhesin A (PsaA) has previously been reported to play a significant role in pneumococcal adherence and colo...

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Veröffentlicht in:	Microbial pathogenesis 2007-05, Vol.42 (5), p.225-236
Hauptverfasser:	Anderton, Julie M., Rajam, Gowrisankar, Romero-Steiner, Sandra, Summer, Susan, Kowalczyk, Andrew P., Carlone, George M., Sampson, Jacquelyn S., Ades, Edwin W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - biosynthesis Adhesins, Bacterial - metabolism Bacterial Adhesion - physiology Bacteriology Biological and medical sciences Cadherins - biosynthesis Cadherins - genetics Cadherins - metabolism Calcium - metabolism Cell Line, Tumor E-cadherin Edetic Acid - pharmacology Epithelial Cells - metabolism Epithelial Cells - microbiology Epithelial Cells - physiology Fundamental and applied biological sciences. Psychology Humans Lipoproteins - antagonists & inhibitors Lipoproteins - biosynthesis Lipoproteins - metabolism Microbiology Nasopharynx - metabolism Nasopharynx - microbiology Nasopharynx - physiology Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Pneumococcal Infections - metabolism Pneumococcal Infections - microbiology PsaA Streptococcus pneumoniae Streptococcus pneumoniae - drug effects Streptococcus pneumoniae - metabolism Streptococcus pneumoniae - pathogenicity Transfection
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