The Anti-thrombotic Active Constituents from Centella asiatica

The in vitro effects of a methanol extract from the aerial parts of Centella asiatica on shear-induced platelet activation and coagulation were assessed after oral administration to rats, by subjecting non-anticoagulated blood to haemostatometry. 3,5-Di-O-caffeoyl quinic acid, 1,5-di-O-caffeoyl quin...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2007, Vol.30(5), pp.935-940
Hauptverfasser:	Satake, Toshiko, Kamiya, Kohei, An, Yin, Taka), Tomomi Oishi(nee, Yamamoto, Junichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	3,5-di-O-caffeoylquinic acid Administration, Oral Animals anti-thrombotic activity Blood Coagulation - drug effects Blood Coagulation Tests - instrumentation Blood Platelets - drug effects Blood Platelets - physiology Centella - chemistry Centella asiatica Fibrinolytic Agents - chemistry Fibrinolytic Agents - isolation & purification Fibrinolytic Agents - pharmacology haemostatometry Male Methanol Molecular Structure non-anticoagulated blood Plant Components, Aerial - chemistry Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Platelet Activation - drug effects Rats Rats, Wistar shear stress Structure-Activity Relationship
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