Osteomalacia revealing Sjögren's syndrome: a case report

The most common renal disease in Sjögren's syndrome is tubulo-interstitial nephritis, responsible for tubular acidosis in around 20 % of patients. Osteomalacia exceptionally occurs as the first manifestation of a renal tubule disorder due to a Sjögren's syndrome. We report a case of a 20-y...

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Veröffentlicht in:La revue de medecine interne 2008-04, Vol.29 (4), p.311-314
Hauptverfasser: Jallouli, M, Frigui, M, Marzouk, S, Kaddour, N, Kechaou, M, Frikha, F, Bahloul, Z
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container_issue 4
container_start_page 311
container_title La revue de medecine interne
container_volume 29
creator Jallouli, M
Frigui, M
Marzouk, S
Kaddour, N
Kechaou, M
Frikha, F
Bahloul, Z
description The most common renal disease in Sjögren's syndrome is tubulo-interstitial nephritis, responsible for tubular acidosis in around 20 % of patients. Osteomalacia exceptionally occurs as the first manifestation of a renal tubule disorder due to a Sjögren's syndrome. We report a case of a 20-year-old woman with tubular acidosis induced osteomalacia secondary to primary Sjögren's syndrome. Improvement was obtained with bicarbonates, vitamin D, calcium and high-dose steroid therapy. During Sjögren's syndrome, osteomalacia can complicate the distal renal tubular acidosis. In spite of the rare cases of osteomalacia revealing Sjögren's syndrome, this auto-immune disease must appear in the list of the aetiologies of osteomalacia.
doi_str_mv 10.1016/j.revmed.2007.09.028
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subjects Acidosis, Renal Tubular - etiology
Adult
Female
Humans
Mobility Limitation
Osteomalacia - etiology
Sjogren's Syndrome - diagnosis
title Osteomalacia revealing Sjögren's syndrome: a case report
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