Directed differentiation of human embryonic stem cells into functional hepatic cells

The differentiation capacity of human embryonic stem cells (hESCs) holds great promise for therapeutic applications. We report a novel three‐stage method to efficiently direct the differentiation of human embryonic stem cells into hepatic cells in serum‐free medium. Human ESCs were first differentia...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2007-05, Vol.45 (5), p.1229-1239
Hauptverfasser:	Cai, Jun, Zhao, Yang, Liu, Yanxia, Ye, Fei, Song, Zhihua, Qin, Han, Meng, Sha, Chen, Yuezhou, Zhou, Rudan, Song, Xijun, Guo, Yushan, Ding, Mingxiao, Deng, Hongkui
Format:	Artikel
Sprache:	eng
Schlagworte:	Activins - pharmacology Biological and medical sciences Bone Morphogenetic Protein 2 Bone Morphogenetic Proteins - pharmacology Cell Differentiation - physiology Culture Media, Serum-Free Embryonic Stem Cells - cytology Embryonic Stem Cells - drug effects Fibroblast Growth Factor 4 - pharmacology Hepacivirus - physiology Hepatocytes - cytology Hepatocytes - physiology Hepatocytes - virology HIV - physiology Human viral diseases Humans Infectious diseases Medical sciences Transforming Growth Factor beta - pharmacology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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