Design and Synthesis of New 2-Substituted-5-[2-(2-halobenzyloxy)phenyl]-1,3,4-oxadiazoles as Anticonvulsant Agents

A new series of 2-substituted-5-[2-(2-halobenzyloxy)phenyl]-1,3,4-oxadiazoles was designed and synthesized as anticonvulsant agents. Electroshock and pentylenetetrazole-induced lethal convulsion tests showed that the introduction of an amino group at position 2 of 1,3,4-oxadiazole ring and a fluoro...

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Veröffentlicht in:Chemical & Pharmaceutical Bulletin 2008/04/01, Vol.56(4), pp.509-512
Hauptverfasser: Zarghi, Afshin, Hajimahdi, Zahra, Mohebbi, Shohreh, Rashidi, Hootesa, Mozaffari, Sasan, Sarraf, Sahar, Faizi, Mehrdad, Tabatabaee, Seyed Abbas, Shafiee, Abbas
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Sprache:eng
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