Airway evaluation and management in 7 children with malignant infantile osteopetrosis before hematopoietic stem cell transplantation

Malignant infantile osteopetrosis (MIOP) is a rare disorder caused by dysfunctional osteoclasts. The classic MIOP features, such as frontal bossing, micrognathia, and small thorax, may place these children at risk for developing obstructive sleep apnea (OSA) and chronic hypoxemia. To objectively doc...

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Veröffentlicht in:	Journal of pediatric hematology/oncology 2008-03, Vol.30 (3), p.225-229
Hauptverfasser:	Kasow, Kimberly A, Stocks, Rose Mary S, Kaste, Sue C, Donepudi, Sreekrishna, Tottenham, Dawn, Schoumacher, Robert A, Horwitz, Edwin M
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Obstruction - diagnosis Airway Obstruction - therapy Apnea - diagnosis Apnea - therapy Cohort Studies Diagnosis, Differential Electrocardiography - methods Female Follow-Up Studies Hematopoietic Stem Cell Transplantation Humans Hypoxia - etiology Infant Male Osteopetrosis - diagnosis Osteopetrosis - therapy Polysomnography - methods Predictive Value of Tests Retrospective Studies Sleep Apnea Syndromes - diagnosis Sleep Apnea Syndromes - therapy Treatment Outcome
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