Differentiation of CD133-Positive Pancreatic Cells Into Insulin-Producing Islet-Like Cell Clusters

Abstract Adult pancreatic stem and progenitor cells could represent an alternative source of insulin-producing tissue for diabetes treatment. In order to identify these cells, we have focused on the human pancreatic cells expressing cell surface molecule CD133, a marker of adult stem cells. We found...

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Veröffentlicht in:	Transplantation proceedings 2008-03, Vol.40 (2), p.415-418
Hauptverfasser:	Koblas, T, Pektorova, L, Zacharovova, K, Berkova, Z, Girman, P, Dovolilova, E, Karasova, L, Saudek, F
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Antigens, CD - analysis Biological and medical sciences C-Peptide - analysis Cell Culture Techniques Cell Differentiation Cell Separation - methods Fundamental and applied biological sciences. Psychology Fundamental immunology Glycoproteins - analysis Humans Islets of Langerhans - cytology Islets of Langerhans - physiology Magnetics Medical sciences Pancreas - cytology Peptides - analysis Reverse Transcriptase Polymerase Chain Reaction RNA - genetics RNA - isolation & purification Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology
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