Severe congenital protein C deficiency: description of a new mutation and prophylactic protein C therapy and in vivo pharmacokinetics

Severe congenital protein C deficiency is a rare life-threatening disorder that presents with purpura fulminans, disseminated intravascular coagulation, and thrombotic complications during the neonatal period. Affected children require acute replacement therapy with fresh frozen plasma or protein C...

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Veröffentlicht in:	Journal of pediatric hematology/oncology 2008-02, Vol.30 (2), p.166-171
Hauptverfasser:	Tcheng, Wendy Y, Dovat, Sinisa, Gurel, Zafer, Donkin, Jennifer, Wong, Wing-Yen
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Female Humans Infant, Newborn Molecular Sequence Data Mutation Protein C - genetics Protein C - pharmacokinetics Protein C - therapeutic use Protein C Deficiency - genetics
Online-Zugang:	Volltext
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