Intermediate-term results of repair for aortic, neoaortic, and truncal valve insufficiency in children
Objective Repair of aortic valve insufficiency is difficult, and durability is relatively unknown in children. This study evaluates the intermediate-term results of repair of the systemic semilunar valve, including the native aortic valve, neoaortic valve (anatomic pulmonary), and truncal valve. Met...
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creator | Hawkins, John A., MD Kouretas, Peter C., MD, PhD Holubkov, Richard, PhD Williams, Richard V., MD Tani, Lloyd Y., MD Su, Jason T., DO Lambert, Linda M., RN Mart, Christopher R., MD Puchalski, Michael D., MD Minich, L. LuAnn, MD |
description | Objective Repair of aortic valve insufficiency is difficult, and durability is relatively unknown in children. This study evaluates the intermediate-term results of repair of the systemic semilunar valve, including the native aortic valve, neoaortic valve (anatomic pulmonary), and truncal valve. Methods We reviewed the records of 54 children (aged 2 days to 18 years) who underwent repair of the functional aortic valve for moderate or greater insufficiency from 1991 to 2005. Valve anatomy was tricuspid aortic in 26 patients, bicuspid aortic in 11 patients, tricuspid neoaortic in 9 patients, bicuspid neoaortic in 1 patient, and truncal valve in 7 patients. Multiple surgical techniques were used in most of the 54 patients, including leaflet plication in 17, leaflet repair in 15, commissuroplasty in 32, pericardial cusp augmentation in 8, and sinus of Valsalva reduction in 3. Results There was 1 early death and no late deaths. Actuarial freedom from reoperation was 68% at 5 years and 58% at 10 years. Freedom from aortic valve replacement was 82% at 5 years and 73% at 10 years. Duration of cardiopulmonary bypass was the most significant risk factor for reoperation with multivariate analysis. Of the 40 patients who have not undergone reoperation, 37 have had follow-up echocardiograms with the latest study (4.5 ± 4.2 years) demonstrating trace to 1+ insufficiency in 23 patients, 1 to 2+ in 12 patients, 2 to 3+ in 1 patient, and 3 to 4+ in 1 patient. Conclusion Repair of the insufficient systemic semilunar valve offers acceptable 10-year freedom from reoperation and functional results, and should be considered for most children. |
doi_str_mv | 10.1016/j.jtcvs.2006.11.051 |
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LuAnn, MD</creator><creatorcontrib>Hawkins, John A., MD ; Kouretas, Peter C., MD, PhD ; Holubkov, Richard, PhD ; Williams, Richard V., MD ; Tani, Lloyd Y., MD ; Su, Jason T., DO ; Lambert, Linda M., RN ; Mart, Christopher R., MD ; Puchalski, Michael D., MD ; Minich, L. LuAnn, MD</creatorcontrib><description>Objective Repair of aortic valve insufficiency is difficult, and durability is relatively unknown in children. This study evaluates the intermediate-term results of repair of the systemic semilunar valve, including the native aortic valve, neoaortic valve (anatomic pulmonary), and truncal valve. Methods We reviewed the records of 54 children (aged 2 days to 18 years) who underwent repair of the functional aortic valve for moderate or greater insufficiency from 1991 to 2005. Valve anatomy was tricuspid aortic in 26 patients, bicuspid aortic in 11 patients, tricuspid neoaortic in 9 patients, bicuspid neoaortic in 1 patient, and truncal valve in 7 patients. Multiple surgical techniques were used in most of the 54 patients, including leaflet plication in 17, leaflet repair in 15, commissuroplasty in 32, pericardial cusp augmentation in 8, and sinus of Valsalva reduction in 3. Results There was 1 early death and no late deaths. Actuarial freedom from reoperation was 68% at 5 years and 58% at 10 years. Freedom from aortic valve replacement was 82% at 5 years and 73% at 10 years. Duration of cardiopulmonary bypass was the most significant risk factor for reoperation with multivariate analysis. Of the 40 patients who have not undergone reoperation, 37 have had follow-up echocardiograms with the latest study (4.5 ± 4.2 years) demonstrating trace to 1+ insufficiency in 23 patients, 1 to 2+ in 12 patients, 2 to 3+ in 1 patient, and 3 to 4+ in 1 patient. Conclusion Repair of the insufficient systemic semilunar valve offers acceptable 10-year freedom from reoperation and functional results, and should be considered for most children.</description><identifier>ISSN: 0022-5223</identifier><identifier>EISSN: 1097-685X</identifier><identifier>DOI: 10.1016/j.jtcvs.2006.11.051</identifier><identifier>PMID: 17467448</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Adolescent ; Aortic Valve - abnormalities ; Aortic Valve - surgery ; Aortic Valve Insufficiency - etiology ; Aortic Valve Insufficiency - surgery ; Cardiothoracic Surgery ; Child ; Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Pulmonary Valve - abnormalities ; Pulmonary Valve - surgery ; Pulmonary Valve Insufficiency - etiology ; Pulmonary Valve Insufficiency - surgery ; Reoperation ; Risk Factors ; Truncus Arteriosus, Persistent - surgery</subject><ispartof>The Journal of thoracic and cardiovascular surgery, 2007-05, Vol.133 (5), p.1311-1317</ispartof><rights>The American Association for Thoracic Surgery</rights><rights>2007 The American Association for Thoracic Surgery</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c490t-71649b15d034a2cf8bfa1583e69c18b544ac39181585e9ebf14c925eb27d8dad3</citedby><cites>FETCH-LOGICAL-c490t-71649b15d034a2cf8bfa1583e69c18b544ac39181585e9ebf14c925eb27d8dad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jtcvs.2006.11.051$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17467448$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hawkins, John A., MD</creatorcontrib><creatorcontrib>Kouretas, Peter C., MD, PhD</creatorcontrib><creatorcontrib>Holubkov, Richard, PhD</creatorcontrib><creatorcontrib>Williams, Richard V., MD</creatorcontrib><creatorcontrib>Tani, Lloyd Y., MD</creatorcontrib><creatorcontrib>Su, Jason T., DO</creatorcontrib><creatorcontrib>Lambert, Linda M., RN</creatorcontrib><creatorcontrib>Mart, Christopher R., MD</creatorcontrib><creatorcontrib>Puchalski, Michael D., MD</creatorcontrib><creatorcontrib>Minich, L. LuAnn, MD</creatorcontrib><title>Intermediate-term results of repair for aortic, neoaortic, and truncal valve insufficiency in children</title><title>The Journal of thoracic and cardiovascular surgery</title><addtitle>J Thorac Cardiovasc Surg</addtitle><description>Objective Repair of aortic valve insufficiency is difficult, and durability is relatively unknown in children. This study evaluates the intermediate-term results of repair of the systemic semilunar valve, including the native aortic valve, neoaortic valve (anatomic pulmonary), and truncal valve. Methods We reviewed the records of 54 children (aged 2 days to 18 years) who underwent repair of the functional aortic valve for moderate or greater insufficiency from 1991 to 2005. Valve anatomy was tricuspid aortic in 26 patients, bicuspid aortic in 11 patients, tricuspid neoaortic in 9 patients, bicuspid neoaortic in 1 patient, and truncal valve in 7 patients. Multiple surgical techniques were used in most of the 54 patients, including leaflet plication in 17, leaflet repair in 15, commissuroplasty in 32, pericardial cusp augmentation in 8, and sinus of Valsalva reduction in 3. Results There was 1 early death and no late deaths. Actuarial freedom from reoperation was 68% at 5 years and 58% at 10 years. Freedom from aortic valve replacement was 82% at 5 years and 73% at 10 years. Duration of cardiopulmonary bypass was the most significant risk factor for reoperation with multivariate analysis. Of the 40 patients who have not undergone reoperation, 37 have had follow-up echocardiograms with the latest study (4.5 ± 4.2 years) demonstrating trace to 1+ insufficiency in 23 patients, 1 to 2+ in 12 patients, 2 to 3+ in 1 patient, and 3 to 4+ in 1 patient. Conclusion Repair of the insufficient systemic semilunar valve offers acceptable 10-year freedom from reoperation and functional results, and should be considered for most children.</description><subject>Adolescent</subject><subject>Aortic Valve - abnormalities</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Insufficiency - etiology</subject><subject>Aortic Valve Insufficiency - surgery</subject><subject>Cardiothoracic Surgery</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Pulmonary Valve - abnormalities</subject><subject>Pulmonary Valve - surgery</subject><subject>Pulmonary Valve Insufficiency - etiology</subject><subject>Pulmonary Valve Insufficiency - surgery</subject><subject>Reoperation</subject><subject>Risk Factors</subject><subject>Truncus Arteriosus, Persistent - surgery</subject><issn>0022-5223</issn><issn>1097-685X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk-LFDEQxYMo7uzqJxCkT-LBblOd9L-DgiyuLix4UMFbkU5XnLSZ7jFJj8y3N70zInjxlJfi1aP4VTH2DHgBHOrXYzFGfQhFyXldABS8ggdsA7xr8rqtvj1kG87LMq_KUlywyxBGznnDoXvMLqCRdSNlu2HmdorkdzRYFSlfZeYpLC6GbDZJ7pX1mZl9pmYfrX6VTTT_kWoasuiXSSuXHZQ7UGansBhjtaVJH9Mv01vrBk_TE_bIKBfo6fm9Yl9v3n-5_pjfffpwe_3uLtey4zFvoJZdD9XAhVSlNm1vFFStoLrT0PaVlEqLDtpUq6ij3oDUXVlRXzZDO6hBXLEXp9y9n38uFCLubNDknEpzLwEbLqXsap6M4mTUfg7Bk8G9tzvljwgcV7w44j1eXPEiACa8qev5OX7pE7O_PWeeyfDyZNja79tf1hOGnXIu2WGNCyAEVggC1qw3JyslHgdLHsM9t7QKTzriMNv_zPL2n37t7GTTMn7QkcI4L35KqBEwlMjx83oM6y2kG0gpvBW_AXvssLQ</recordid><startdate>20070501</startdate><enddate>20070501</enddate><creator>Hawkins, John A., MD</creator><creator>Kouretas, Peter C., MD, PhD</creator><creator>Holubkov, Richard, PhD</creator><creator>Williams, Richard V., MD</creator><creator>Tani, Lloyd Y., MD</creator><creator>Su, Jason T., DO</creator><creator>Lambert, Linda M., RN</creator><creator>Mart, Christopher R., MD</creator><creator>Puchalski, Michael D., MD</creator><creator>Minich, L. LuAnn, MD</creator><general>Mosby, Inc</general><general>AATS/WTSA</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070501</creationdate><title>Intermediate-term results of repair for aortic, neoaortic, and truncal valve insufficiency in children</title><author>Hawkins, John A., MD ; Kouretas, Peter C., MD, PhD ; Holubkov, Richard, PhD ; Williams, Richard V., MD ; Tani, Lloyd Y., MD ; Su, Jason T., DO ; Lambert, Linda M., RN ; Mart, Christopher R., MD ; Puchalski, Michael D., MD ; Minich, L. LuAnn, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c490t-71649b15d034a2cf8bfa1583e69c18b544ac39181585e9ebf14c925eb27d8dad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Aortic Valve - abnormalities</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Insufficiency - etiology</topic><topic>Aortic Valve Insufficiency - surgery</topic><topic>Cardiothoracic Surgery</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Pulmonary Valve - abnormalities</topic><topic>Pulmonary Valve - surgery</topic><topic>Pulmonary Valve Insufficiency - etiology</topic><topic>Pulmonary Valve Insufficiency - surgery</topic><topic>Reoperation</topic><topic>Risk Factors</topic><topic>Truncus Arteriosus, Persistent - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hawkins, John A., MD</creatorcontrib><creatorcontrib>Kouretas, Peter C., MD, PhD</creatorcontrib><creatorcontrib>Holubkov, Richard, PhD</creatorcontrib><creatorcontrib>Williams, Richard V., MD</creatorcontrib><creatorcontrib>Tani, Lloyd Y., MD</creatorcontrib><creatorcontrib>Su, Jason T., DO</creatorcontrib><creatorcontrib>Lambert, Linda M., RN</creatorcontrib><creatorcontrib>Mart, Christopher R., MD</creatorcontrib><creatorcontrib>Puchalski, Michael D., MD</creatorcontrib><creatorcontrib>Minich, L. LuAnn, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hawkins, John A., MD</au><au>Kouretas, Peter C., MD, PhD</au><au>Holubkov, Richard, PhD</au><au>Williams, Richard V., MD</au><au>Tani, Lloyd Y., MD</au><au>Su, Jason T., DO</au><au>Lambert, Linda M., RN</au><au>Mart, Christopher R., MD</au><au>Puchalski, Michael D., MD</au><au>Minich, L. LuAnn, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intermediate-term results of repair for aortic, neoaortic, and truncal valve insufficiency in children</atitle><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle><addtitle>J Thorac Cardiovasc Surg</addtitle><date>2007-05-01</date><risdate>2007</risdate><volume>133</volume><issue>5</issue><spage>1311</spage><epage>1317</epage><pages>1311-1317</pages><issn>0022-5223</issn><eissn>1097-685X</eissn><abstract>Objective Repair of aortic valve insufficiency is difficult, and durability is relatively unknown in children. This study evaluates the intermediate-term results of repair of the systemic semilunar valve, including the native aortic valve, neoaortic valve (anatomic pulmonary), and truncal valve. Methods We reviewed the records of 54 children (aged 2 days to 18 years) who underwent repair of the functional aortic valve for moderate or greater insufficiency from 1991 to 2005. Valve anatomy was tricuspid aortic in 26 patients, bicuspid aortic in 11 patients, tricuspid neoaortic in 9 patients, bicuspid neoaortic in 1 patient, and truncal valve in 7 patients. Multiple surgical techniques were used in most of the 54 patients, including leaflet plication in 17, leaflet repair in 15, commissuroplasty in 32, pericardial cusp augmentation in 8, and sinus of Valsalva reduction in 3. Results There was 1 early death and no late deaths. Actuarial freedom from reoperation was 68% at 5 years and 58% at 10 years. Freedom from aortic valve replacement was 82% at 5 years and 73% at 10 years. Duration of cardiopulmonary bypass was the most significant risk factor for reoperation with multivariate analysis. Of the 40 patients who have not undergone reoperation, 37 have had follow-up echocardiograms with the latest study (4.5 ± 4.2 years) demonstrating trace to 1+ insufficiency in 23 patients, 1 to 2+ in 12 patients, 2 to 3+ in 1 patient, and 3 to 4+ in 1 patient. Conclusion Repair of the insufficient systemic semilunar valve offers acceptable 10-year freedom from reoperation and functional results, and should be considered for most children.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>17467448</pmid><doi>10.1016/j.jtcvs.2006.11.051</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Aortic Valve - abnormalities Aortic Valve - surgery Aortic Valve Insufficiency - etiology Aortic Valve Insufficiency - surgery Cardiothoracic Surgery Child Child, Preschool Humans Infant Infant, Newborn Pulmonary Valve - abnormalities Pulmonary Valve - surgery Pulmonary Valve Insufficiency - etiology Pulmonary Valve Insufficiency - surgery Reoperation Risk Factors Truncus Arteriosus, Persistent - surgery |
title | Intermediate-term results of repair for aortic, neoaortic, and truncal valve insufficiency in children |
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