β-Blockers and Coronary Flow Reserve: The Importance of a Vasodilatory Action

Coronary flow reserve (CFR) is the maximal increase in coronary blood flow (CBF) above its resting level for a given perfusion pressure when coronary vasculature is maximally dilated. Normally, hyperaemic CBF reaches values at least 2- to 3-fold greater than resting CBF. Reduction of CFR is mainly d...

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Veröffentlicht in:	Drugs (New York, N.Y.) N.Y.), 2008, Vol.68 (5), p.579-550
Hauptverfasser:	Galderisi, Maurizio, D’Errico, Arcangelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - pharmacology Antianginal agents. Coronary vasodilator agents Biological and medical sciences Cardiology. Vascular system Cardiovascular system Coronary Circulation - drug effects Coronary heart disease Current Opinion Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Heart Humans Internal Medicine Medical sciences Medicine Medicine & Public Health Microcirculation - drug effects Pharmacology. Drug treatments Pharmacology/Toxicology Pharmacotherapy Vasodilator Agents - pharmacology
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