Predictive genetic testing of children for adult-onset diseases and psychological harm
One of the central arguments given to resist testing currently healthy, asymptomatic children for adult-onset diseases is that they may be psychologically harmed by the knowledge gained from such tests. In this discussion I examine two of the most serious arguments: children who are tested may face...
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description | One of the central arguments given to resist testing currently healthy, asymptomatic children for adult-onset diseases is that they may be psychologically harmed by the knowledge gained from such tests. In this discussion I examine two of the most serious arguments: children who are tested may face limited futures, and that testing may result in damage to the child’s self esteem (where the test result returns a positive diagnosis). I claim that these arguments do not stand up to critical evaluation. In conclusion, whilst I do not suggest that all at-risk children should be tested for adult-onset diseases we ought to listen carefully to some parental requests for such testing because the putative psychological harms may not be as significant or likely as initially thought. This is because parents generally have the best interests of their children at heart and if they are properly supported and educated about predictive genetic testing and the possible consequences, then the risk of psychological harms occurring may be ameliorated. |
doi_str_mv | 10.1136/jme.2006.019802 |
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In this discussion I examine two of the most serious arguments: children who are tested may face limited futures, and that testing may result in damage to the child’s self esteem (where the test result returns a positive diagnosis). I claim that these arguments do not stand up to critical evaluation. In conclusion, whilst I do not suggest that all at-risk children should be tested for adult-onset diseases we ought to listen carefully to some parental requests for such testing because the putative psychological harms may not be as significant or likely as initially thought. 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In this discussion I examine two of the most serious arguments: children who are tested may face limited futures, and that testing may result in damage to the child’s self esteem (where the test result returns a positive diagnosis). I claim that these arguments do not stand up to critical evaluation. In conclusion, whilst I do not suggest that all at-risk children should be tested for adult-onset diseases we ought to listen carefully to some parental requests for such testing because the putative psychological harms may not be as significant or likely as initially thought. This is because parents generally have the best interests of their children at heart and if they are properly supported and educated about predictive genetic testing and the possible consequences, then the risk of psychological harms occurring may be ameliorated.</description><subject>Adult</subject><subject>Adults</subject><subject>Age of Onset</subject><subject>Bioethics</subject><subject>Child</subject><subject>Child psychology</subject><subject>Children</subject><subject>Children & youth</subject><subject>Diagnosis</subject><subject>Disease</subject><subject>Diseases</subject><subject>Families & family life</subject><subject>Female</subject><subject>Genetic diseases</subject><subject>Genetic Diseases, Inborn - diagnosis</subject><subject>Genetic Diseases, Inborn - psychology</subject><subject>Genetic Predisposition to Disease - psychology</subject><subject>Genetic screening</subject><subject>Genetic testing</subject><subject>Genetic Testing - ethics</subject><subject>Genetic Testing - psychology</subject><subject>Global Medical Ethics</subject><subject>Higher education</subject><subject>Human genetics</subject><subject>Humans</subject><subject>Huntington disease</subject><subject>Male</subject><subject>Medical genetics</subject><subject>Methods</subject><subject>Minors - psychology</subject><subject>Mutation</subject><subject>Parent-Child Relations</subject><subject>Parental Consent</subject><subject>Parents</subject><subject>Parents & parenting</subject><subject>Practice Guidelines as Topic</subject><subject>predictive genetic testing</subject><subject>psychological harm</subject><subject>Risk Assessment</subject><subject>Self Concept</subject><subject>Self esteem</subject><subject>Youths at risk</subject><issn>0306-6800</issn><issn>1473-4257</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AVQMV</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>K50</sourceid><sourceid>M1D</sourceid><sourceid>M2O</sourceid><recordid>eNqF0Utv1DAUBeAIgehQWLMCWUJigZSpH3GcLEvESyq0gtKt5dg3GQcnHuwE0X-PRxm1Ept648X9bB37ZNlLgreEsPJsGGFLMS63mNQVpo-yDSkEywvKxeNsgxku87LC-CR7FuOA06JV_TQ7IRUTPA022c1VAGP1bP8A6mGC2Wo0Q5zt1CPfIb2zzgSYUOcDUmZxc-6nCDMyNoKKEJGaDNrHW73zzvdWK4d2KozPsyedchFeHPfT7OfHD9fN5_zi8tOX5vwib4tKzLnoSFFrUypdaKErrjvacaoUB2Z4yVtMjTJcFMbUClelYIy2gOu2M9joyhh2mr1d790H_3tJueVoowbn1AR-iVLgomB1zR-EJBlSlUWCb_6Dg1_ClB4hiagIFpRSkVS-ql45kHbSfprh76y9c9CDTG9sLuV5OlBwghlL_mz1OvgYA3RyH-yowq0kWB6alKlJeWhSrk2mE6-POZZ2BHPvj9Ul8GoFQ5x9uJtTIQ7X4PuINqZod3MVfsn0kYLLbzeNfN9cNfj6-1f5I_l3q2_H4cF0_wD5Er7T</recordid><startdate>20080401</startdate><enddate>20080401</enddate><creator>Malpas, P J</creator><general>BMJ Publishing Group Ltd and Institute of Medical Ethics</general><general>Institute of Medical Ethics and BMJ Publishing Group</general><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>88J</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>AABKS</scope><scope>ABSDQ</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AVQMV</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K50</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1D</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M2R</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7U1</scope><scope>7U2</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20080401</creationdate><title>Predictive genetic testing of children for adult-onset diseases and psychological harm</title><author>Malpas, P J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b487t-7f149cd6ac4c7c85cf2f52aa5e3d565b02dad574dd9a0867332be09bfd0dc8dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Adults</topic><topic>Age of Onset</topic><topic>Bioethics</topic><topic>Child</topic><topic>Child psychology</topic><topic>Children</topic><topic>Children & youth</topic><topic>Diagnosis</topic><topic>Disease</topic><topic>Diseases</topic><topic>Families & family life</topic><topic>Female</topic><topic>Genetic diseases</topic><topic>Genetic Diseases, Inborn - diagnosis</topic><topic>Genetic Diseases, Inborn - psychology</topic><topic>Genetic Predisposition to Disease - psychology</topic><topic>Genetic screening</topic><topic>Genetic testing</topic><topic>Genetic Testing - ethics</topic><topic>Genetic Testing - psychology</topic><topic>Global Medical Ethics</topic><topic>Higher education</topic><topic>Human genetics</topic><topic>Humans</topic><topic>Huntington disease</topic><topic>Male</topic><topic>Medical genetics</topic><topic>Methods</topic><topic>Minors - psychology</topic><topic>Mutation</topic><topic>Parent-Child Relations</topic><topic>Parental Consent</topic><topic>Parents</topic><topic>Parents & parenting</topic><topic>Practice Guidelines as Topic</topic><topic>predictive genetic testing</topic><topic>psychological harm</topic><topic>Risk Assessment</topic><topic>Self Concept</topic><topic>Self esteem</topic><topic>Youths at risk</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Malpas, P J</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Philosophy Collection</collection><collection>Philosophy Database</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>Arts Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Art, Design & Architecture Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Arts & Humanities Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Social Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medical ethics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Malpas, P J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictive genetic testing of children for adult-onset diseases and psychological harm</atitle><jtitle>Journal of medical ethics</jtitle><addtitle>J Med Ethics</addtitle><date>2008-04-01</date><risdate>2008</risdate><volume>34</volume><issue>4</issue><spage>275</spage><epage>278</epage><pages>275-278</pages><issn>0306-6800</issn><eissn>1473-4257</eissn><coden>JMETDR</coden><abstract>One of the central arguments given to resist testing currently healthy, asymptomatic children for adult-onset diseases is that they may be psychologically harmed by the knowledge gained from such tests. In this discussion I examine two of the most serious arguments: children who are tested may face limited futures, and that testing may result in damage to the child’s self esteem (where the test result returns a positive diagnosis). I claim that these arguments do not stand up to critical evaluation. In conclusion, whilst I do not suggest that all at-risk children should be tested for adult-onset diseases we ought to listen carefully to some parental requests for such testing because the putative psychological harms may not be as significant or likely as initially thought. This is because parents generally have the best interests of their children at heart and if they are properly supported and educated about predictive genetic testing and the possible consequences, then the risk of psychological harms occurring may be ameliorated.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and Institute of Medical Ethics</pub><pmid>18375680</pmid><doi>10.1136/jme.2006.019802</doi><tpages>4</tpages></addata></record> |
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subjects | Adult Adults Age of Onset Bioethics Child Child psychology Children Children & youth Diagnosis Disease Diseases Families & family life Female Genetic diseases Genetic Diseases, Inborn - diagnosis Genetic Diseases, Inborn - psychology Genetic Predisposition to Disease - psychology Genetic screening Genetic testing Genetic Testing - ethics Genetic Testing - psychology Global Medical Ethics Higher education Human genetics Humans Huntington disease Male Medical genetics Methods Minors - psychology Mutation Parent-Child Relations Parental Consent Parents Parents & parenting Practice Guidelines as Topic predictive genetic testing psychological harm Risk Assessment Self Concept Self esteem Youths at risk |
title | Predictive genetic testing of children for adult-onset diseases and psychological harm |
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