Assessment of Diet‐induced Obese Rats as an Obesity Model by Comparative Functional Genomics

Objective: We applied a comparative functional genomics approach to evaluate whether diet‐induced obese (DIO) rats serve as an effective obesity model. Methods and Procedures: Gene‐expression profiles of epididymal fat from DIO and lean rats were generated using microarrays and compared with the pub...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2008-04, Vol.16 (4), p.811-818
Hauptverfasser:	Li, Shuyu, Zhang, Hong‐Yan, Hu, Charlie C., Lawrence, Frank, Gallagher, Kelly E., Surapaneni, Anupama, Estrem, Shawn T., Calley, John N., Varga, Gabor, Dow, Ernst R., Chen, Yanyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - physiology Animal Feed Animals Body Composition - genetics Body Weight - genetics Cells, Cultured Dietary Fats - pharmacology Dietary Sucrose - pharmacology Disease Models, Animal Eating - genetics Gene Expression Profiling Genetic Predisposition to Disease Genomics Humans Indians, North American Insulin Resistance - genetics Male Obesity - etiology Obesity - genetics Obesity - metabolism Oligonucleotide Array Sequence Analysis Rats Rats, Long-Evans
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