Prevalence of some risk factors in children with epilepsy compared to their controls

Summary Aim The goal of this case–control study was to identify the significance of certain risk factors for epilepsy in Turkey. Method A total of 805 cases, aged 1–16 years, followed-up for epilepsy at the Pediatric Neurology Department and a control group consisting of 846 age-matched cases withou...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Seizure (London, England) England), 2007-06, Vol.16 (4), p.338-344
Hauptverfasser: Cansu, Ali, Serdaroğlu, Ayşe, Yüksel, Deniz, Doğan, Vehbi, Özkan, Seçil, Hırfanoğlu, Tuğba, Şenbil, Nesrin, Gücüyener, Kıvılcım, Soysal, Şebnem, Çamurdan, Aysu, Gürer, Yavuz Kemal
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 344
container_issue 4
container_start_page 338
container_title Seizure (London, England)
container_volume 16
creator Cansu, Ali
Serdaroğlu, Ayşe
Yüksel, Deniz
Doğan, Vehbi
Özkan, Seçil
Hırfanoğlu, Tuğba
Şenbil, Nesrin
Gücüyener, Kıvılcım
Soysal, Şebnem
Çamurdan, Aysu
Gürer, Yavuz Kemal
description Summary Aim The goal of this case–control study was to identify the significance of certain risk factors for epilepsy in Turkey. Method A total of 805 cases, aged 1–16 years, followed-up for epilepsy at the Pediatric Neurology Department and a control group consisting of 846 age-matched cases without epilepsy were included in the study. The risk factors examined were gender, neurological impairment, febrile convulsion, head trauma, central nervous system infections, parental consanguinity, family history of epilepsy, prenatal and natal risk and newborn jaundice. Data regarding the investigated epilepsy risk factors were obtained through a questionnaire via personal interviews and the medical records and were assessed using univariate and multivariate analysis. Result Univariate analysis showed an increased risk for epilepsy with a history of atypical febrile seizure (21.97-fold), severe and moderate head injury (27.76- and 7.09-fold respectively), CNS infection (4.76-fold), history of epilepsy in first-, second- or third-degree relatives (6.42-, 3.09- and 2.66-fold, respectively), presence of maternal hypertension (4.31-fold), an apgar score ≤6 at any time (7.78-fold) and neonatal jaundice (3.12-fold). Abnormal neurological signs increased the epilepsy risk 5.92 times in univariate analysis and 30.26 times in multivariate analysis. Conclusion The most important risk factors for epilepsy in this study were neurological impairment, history of atypical febrile seizures, severe head injury and a low apgar score. Other important risk factors were moderate head trauma and a history of epilepsy in the family.
doi_str_mv 10.1016/j.seizure.2007.02.003
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70439500</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S105913110700043X</els_id><sourcerecordid>70439500</sourcerecordid><originalsourceid>FETCH-LOGICAL-c465t-5b467996309c68b62578decae89cc92a45f46244c1c2a9e1ebee846f63a690983</originalsourceid><addsrcrecordid>eNqFkU9r3DAQxUVoaZJtP0KKTr3Z1T_L1qUhhKQpBBpoCr0JrTxmtZEtR7ITNp--MrsQyCWnGYb3ZpjfQ-iMkpISKr9vywTuZY5QMkLqkrCSEH6ETmjFWcFk03zIPalUQTmlx-g0pS0hRAnKP6FjWnNFlaIn6P4uwpPxMFjAocMp9ICjSw-4M3YKMWE3YLtxvo0w4Gc3bTCMzsOYdtiGfjQRWjwFPG3AxTwZphh8-ow-dsYn-HKoK_T3-ur-8qa4_f3z1-XFbWGFrKaiWgtZKyU5UVY2a8mqumnBGmiUtYoZUXVCMiEstcwooLAGaITsJDdSEdXwFfq23zvG8DhDmnTvkgXvzQBhTromgqsqc1mhai-0MaQUodNjdL2JO02JXnDqrT7g1AtOTZjOtuz7ejgwr3toX10HfllwvhdAfvPJQdTJugVm6yLYSbfBvXvix5sN1rvBWeMfYAdpG-Y4ZIaa6pQN-s-S6RIpqXOcgv_j_wHRQ56k</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70439500</pqid></control><display><type>article</type><title>Prevalence of some risk factors in children with epilepsy compared to their controls</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Cansu, Ali ; Serdaroğlu, Ayşe ; Yüksel, Deniz ; Doğan, Vehbi ; Özkan, Seçil ; Hırfanoğlu, Tuğba ; Şenbil, Nesrin ; Gücüyener, Kıvılcım ; Soysal, Şebnem ; Çamurdan, Aysu ; Gürer, Yavuz Kemal</creator><creatorcontrib>Cansu, Ali ; Serdaroğlu, Ayşe ; Yüksel, Deniz ; Doğan, Vehbi ; Özkan, Seçil ; Hırfanoğlu, Tuğba ; Şenbil, Nesrin ; Gücüyener, Kıvılcım ; Soysal, Şebnem ; Çamurdan, Aysu ; Gürer, Yavuz Kemal</creatorcontrib><description>Summary Aim The goal of this case–control study was to identify the significance of certain risk factors for epilepsy in Turkey. Method A total of 805 cases, aged 1–16 years, followed-up for epilepsy at the Pediatric Neurology Department and a control group consisting of 846 age-matched cases without epilepsy were included in the study. The risk factors examined were gender, neurological impairment, febrile convulsion, head trauma, central nervous system infections, parental consanguinity, family history of epilepsy, prenatal and natal risk and newborn jaundice. Data regarding the investigated epilepsy risk factors were obtained through a questionnaire via personal interviews and the medical records and were assessed using univariate and multivariate analysis. Result Univariate analysis showed an increased risk for epilepsy with a history of atypical febrile seizure (21.97-fold), severe and moderate head injury (27.76- and 7.09-fold respectively), CNS infection (4.76-fold), history of epilepsy in first-, second- or third-degree relatives (6.42-, 3.09- and 2.66-fold, respectively), presence of maternal hypertension (4.31-fold), an apgar score ≤6 at any time (7.78-fold) and neonatal jaundice (3.12-fold). Abnormal neurological signs increased the epilepsy risk 5.92 times in univariate analysis and 30.26 times in multivariate analysis. Conclusion The most important risk factors for epilepsy in this study were neurological impairment, history of atypical febrile seizures, severe head injury and a low apgar score. Other important risk factors were moderate head trauma and a history of epilepsy in the family.</description><identifier>ISSN: 1059-1311</identifier><identifier>EISSN: 1532-2688</identifier><identifier>DOI: 10.1016/j.seizure.2007.02.003</identifier><identifier>PMID: 17391991</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Apgar Score ; Case-Control Studies ; Child ; Child, Preschool ; Children ; Craniocerebral Trauma - complications ; Epilepsy ; Epilepsy - epidemiology ; Epilepsy - etiology ; Female ; Genetic Predisposition to Disease ; Humans ; Infant ; Infant, Newborn ; Male ; Nervous System Diseases - complications ; Neurology ; Prevalence ; Risk Factors ; Seizures, Febrile - complications ; Turkey</subject><ispartof>Seizure (London, England), 2007-06, Vol.16 (4), p.338-344</ispartof><rights>British Epilepsy Association</rights><rights>2007 British Epilepsy Association</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-5b467996309c68b62578decae89cc92a45f46244c1c2a9e1ebee846f63a690983</citedby><cites>FETCH-LOGICAL-c465t-5b467996309c68b62578decae89cc92a45f46244c1c2a9e1ebee846f63a690983</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.seizure.2007.02.003$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17391991$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cansu, Ali</creatorcontrib><creatorcontrib>Serdaroğlu, Ayşe</creatorcontrib><creatorcontrib>Yüksel, Deniz</creatorcontrib><creatorcontrib>Doğan, Vehbi</creatorcontrib><creatorcontrib>Özkan, Seçil</creatorcontrib><creatorcontrib>Hırfanoğlu, Tuğba</creatorcontrib><creatorcontrib>Şenbil, Nesrin</creatorcontrib><creatorcontrib>Gücüyener, Kıvılcım</creatorcontrib><creatorcontrib>Soysal, Şebnem</creatorcontrib><creatorcontrib>Çamurdan, Aysu</creatorcontrib><creatorcontrib>Gürer, Yavuz Kemal</creatorcontrib><title>Prevalence of some risk factors in children with epilepsy compared to their controls</title><title>Seizure (London, England)</title><addtitle>Seizure</addtitle><description>Summary Aim The goal of this case–control study was to identify the significance of certain risk factors for epilepsy in Turkey. Method A total of 805 cases, aged 1–16 years, followed-up for epilepsy at the Pediatric Neurology Department and a control group consisting of 846 age-matched cases without epilepsy were included in the study. The risk factors examined were gender, neurological impairment, febrile convulsion, head trauma, central nervous system infections, parental consanguinity, family history of epilepsy, prenatal and natal risk and newborn jaundice. Data regarding the investigated epilepsy risk factors were obtained through a questionnaire via personal interviews and the medical records and were assessed using univariate and multivariate analysis. Result Univariate analysis showed an increased risk for epilepsy with a history of atypical febrile seizure (21.97-fold), severe and moderate head injury (27.76- and 7.09-fold respectively), CNS infection (4.76-fold), history of epilepsy in first-, second- or third-degree relatives (6.42-, 3.09- and 2.66-fold, respectively), presence of maternal hypertension (4.31-fold), an apgar score ≤6 at any time (7.78-fold) and neonatal jaundice (3.12-fold). Abnormal neurological signs increased the epilepsy risk 5.92 times in univariate analysis and 30.26 times in multivariate analysis. Conclusion The most important risk factors for epilepsy in this study were neurological impairment, history of atypical febrile seizures, severe head injury and a low apgar score. Other important risk factors were moderate head trauma and a history of epilepsy in the family.</description><subject>Adolescent</subject><subject>Apgar Score</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Craniocerebral Trauma - complications</subject><subject>Epilepsy</subject><subject>Epilepsy - epidemiology</subject><subject>Epilepsy - etiology</subject><subject>Female</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Nervous System Diseases - complications</subject><subject>Neurology</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Seizures, Febrile - complications</subject><subject>Turkey</subject><issn>1059-1311</issn><issn>1532-2688</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9r3DAQxUVoaZJtP0KKTr3Z1T_L1qUhhKQpBBpoCr0JrTxmtZEtR7ITNp--MrsQyCWnGYb3ZpjfQ-iMkpISKr9vywTuZY5QMkLqkrCSEH6ETmjFWcFk03zIPalUQTmlx-g0pS0hRAnKP6FjWnNFlaIn6P4uwpPxMFjAocMp9ICjSw-4M3YKMWE3YLtxvo0w4Gc3bTCMzsOYdtiGfjQRWjwFPG3AxTwZphh8-ow-dsYn-HKoK_T3-ur-8qa4_f3z1-XFbWGFrKaiWgtZKyU5UVY2a8mqumnBGmiUtYoZUXVCMiEstcwooLAGaITsJDdSEdXwFfq23zvG8DhDmnTvkgXvzQBhTromgqsqc1mhai-0MaQUodNjdL2JO02JXnDqrT7g1AtOTZjOtuz7ejgwr3toX10HfllwvhdAfvPJQdTJugVm6yLYSbfBvXvix5sN1rvBWeMfYAdpG-Y4ZIaa6pQN-s-S6RIpqXOcgv_j_wHRQ56k</recordid><startdate>20070601</startdate><enddate>20070601</enddate><creator>Cansu, Ali</creator><creator>Serdaroğlu, Ayşe</creator><creator>Yüksel, Deniz</creator><creator>Doğan, Vehbi</creator><creator>Özkan, Seçil</creator><creator>Hırfanoğlu, Tuğba</creator><creator>Şenbil, Nesrin</creator><creator>Gücüyener, Kıvılcım</creator><creator>Soysal, Şebnem</creator><creator>Çamurdan, Aysu</creator><creator>Gürer, Yavuz Kemal</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070601</creationdate><title>Prevalence of some risk factors in children with epilepsy compared to their controls</title><author>Cansu, Ali ; Serdaroğlu, Ayşe ; Yüksel, Deniz ; Doğan, Vehbi ; Özkan, Seçil ; Hırfanoğlu, Tuğba ; Şenbil, Nesrin ; Gücüyener, Kıvılcım ; Soysal, Şebnem ; Çamurdan, Aysu ; Gürer, Yavuz Kemal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-5b467996309c68b62578decae89cc92a45f46244c1c2a9e1ebee846f63a690983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Apgar Score</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Craniocerebral Trauma - complications</topic><topic>Epilepsy</topic><topic>Epilepsy - epidemiology</topic><topic>Epilepsy - etiology</topic><topic>Female</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Nervous System Diseases - complications</topic><topic>Neurology</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Seizures, Febrile - complications</topic><topic>Turkey</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cansu, Ali</creatorcontrib><creatorcontrib>Serdaroğlu, Ayşe</creatorcontrib><creatorcontrib>Yüksel, Deniz</creatorcontrib><creatorcontrib>Doğan, Vehbi</creatorcontrib><creatorcontrib>Özkan, Seçil</creatorcontrib><creatorcontrib>Hırfanoğlu, Tuğba</creatorcontrib><creatorcontrib>Şenbil, Nesrin</creatorcontrib><creatorcontrib>Gücüyener, Kıvılcım</creatorcontrib><creatorcontrib>Soysal, Şebnem</creatorcontrib><creatorcontrib>Çamurdan, Aysu</creatorcontrib><creatorcontrib>Gürer, Yavuz Kemal</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seizure (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cansu, Ali</au><au>Serdaroğlu, Ayşe</au><au>Yüksel, Deniz</au><au>Doğan, Vehbi</au><au>Özkan, Seçil</au><au>Hırfanoğlu, Tuğba</au><au>Şenbil, Nesrin</au><au>Gücüyener, Kıvılcım</au><au>Soysal, Şebnem</au><au>Çamurdan, Aysu</au><au>Gürer, Yavuz Kemal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of some risk factors in children with epilepsy compared to their controls</atitle><jtitle>Seizure (London, England)</jtitle><addtitle>Seizure</addtitle><date>2007-06-01</date><risdate>2007</risdate><volume>16</volume><issue>4</issue><spage>338</spage><epage>344</epage><pages>338-344</pages><issn>1059-1311</issn><eissn>1532-2688</eissn><abstract>Summary Aim The goal of this case–control study was to identify the significance of certain risk factors for epilepsy in Turkey. Method A total of 805 cases, aged 1–16 years, followed-up for epilepsy at the Pediatric Neurology Department and a control group consisting of 846 age-matched cases without epilepsy were included in the study. The risk factors examined were gender, neurological impairment, febrile convulsion, head trauma, central nervous system infections, parental consanguinity, family history of epilepsy, prenatal and natal risk and newborn jaundice. Data regarding the investigated epilepsy risk factors were obtained through a questionnaire via personal interviews and the medical records and were assessed using univariate and multivariate analysis. Result Univariate analysis showed an increased risk for epilepsy with a history of atypical febrile seizure (21.97-fold), severe and moderate head injury (27.76- and 7.09-fold respectively), CNS infection (4.76-fold), history of epilepsy in first-, second- or third-degree relatives (6.42-, 3.09- and 2.66-fold, respectively), presence of maternal hypertension (4.31-fold), an apgar score ≤6 at any time (7.78-fold) and neonatal jaundice (3.12-fold). Abnormal neurological signs increased the epilepsy risk 5.92 times in univariate analysis and 30.26 times in multivariate analysis. Conclusion The most important risk factors for epilepsy in this study were neurological impairment, history of atypical febrile seizures, severe head injury and a low apgar score. Other important risk factors were moderate head trauma and a history of epilepsy in the family.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>17391991</pmid><doi>10.1016/j.seizure.2007.02.003</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1059-1311
ispartof Seizure (London, England), 2007-06, Vol.16 (4), p.338-344
issn 1059-1311
1532-2688
language eng
recordid cdi_proquest_miscellaneous_70439500
source MEDLINE; Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals
subjects Adolescent
Apgar Score
Case-Control Studies
Child
Child, Preschool
Children
Craniocerebral Trauma - complications
Epilepsy
Epilepsy - epidemiology
Epilepsy - etiology
Female
Genetic Predisposition to Disease
Humans
Infant
Infant, Newborn
Male
Nervous System Diseases - complications
Neurology
Prevalence
Risk Factors
Seizures, Febrile - complications
Turkey
title Prevalence of some risk factors in children with epilepsy compared to their controls
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T17%3A54%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20of%20some%20risk%20factors%20in%20children%20with%20epilepsy%20compared%20to%20their%20controls&rft.jtitle=Seizure%20(London,%20England)&rft.au=Cansu,%20Ali&rft.date=2007-06-01&rft.volume=16&rft.issue=4&rft.spage=338&rft.epage=344&rft.pages=338-344&rft.issn=1059-1311&rft.eissn=1532-2688&rft_id=info:doi/10.1016/j.seizure.2007.02.003&rft_dat=%3Cproquest_cross%3E70439500%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70439500&rft_id=info:pmid/17391991&rft_els_id=1_s2_0_S105913110700043X&rfr_iscdi=true