Lacking thyroid hormone receptor β gene does not influence alterations in peripheral thyroid hormone metabolism during acute illness

The downregulation of liver deiodinase type 1 (D1) is supposed to be one of the mechanisms behind the decrease in serum tri-iodothyronine (T3) observed during non-thyroidal illness (NTI). Liver D1 mRNA expression is positively regulated by T3, mainly via the thyroid hormone receptor (TR)β1. One migh...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of endocrinology 2008-04, Vol.197 (1), p.151-158
Hauptverfasser:	Kwakkel, J, Chassande, O, van Beeren, H C, Wiersinga, W M, Boelen, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Biological and medical sciences Cell receptors Cell structures and functions Female Fundamental and applied biological sciences. Psychology Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Interleukin-1beta - genetics Iodide Peroxidase - analysis Iodide Peroxidase - genetics Iodothyronine Deiodinase Type II Lipopolysaccharides - pharmacology Liver - enzymology Male Mice Molecular and cellular biology Regular papers Thyroid Hormone Receptors beta - genetics Thyroid Hormone Receptors beta - physiology Thyroid Hormones - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!