The Role of Imatinib Mesylate in Adjuvant Therapy of Extra-abdominal Desmoid Tumors

Background: Extra-abdominal desmoid tumors are rare neoplasms with variable biological behavior. The mainstay of treatment is surgery. Complementary treatment with tyrosine-kinase receptor inhibitor drugs, particularly imatinib mesylate, has been reported in the literature. The purpose of this study...

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Veröffentlicht in:	Anticancer research 2007-03, Vol.27 (2), p.1143-1147
Hauptverfasser:	IOANNOU, Markos, DEMERTZIS, Nikolaos, IAKOVIDOU, Ioanna, KOTTAKIS, Stamatios
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antineoplastic Agents - therapeutic use Benzamides Biological and medical sciences Dermatology Female Fibromatosis, Aggressive - drug therapy Fibromatosis, Aggressive - metabolism Humans Imatinib Mesylate Male Medical sciences Middle Aged Piperazines - therapeutic use Proto-Oncogene Proteins c-kit - biosynthesis Pyrimidines - therapeutic use Receptor, Platelet-Derived Growth Factor alpha - biosynthesis Receptor, Platelet-Derived Growth Factor beta - biosynthesis Tumors Tumors of the skin and soft tissue. Premalignant lesions
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