Type II Pneumocyte-Restricted Green Fluorescent Protein Expression After Lentiviral Transduction of Lung Epithelial Cells

Type II alveolar epithelial (AT2) cell-specific reporter expression has been highly useful in the study of embryology and alveolar regeneration in transgenic mice. Technologies enabling efficient gene transfer and cell type-restricted transgene expression in AT2 cells would allow for correction of A...

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Veröffentlicht in:	Human gene therapy 2008, Vol.19 (1), p.39-51
Hauptverfasser:	WUNDERLICH, Stephanie, GRUH, Ina, WINKLER, Monica E, BEIER, Jennifer, RADTKE, Kerstin, SCHMIEDL, Andreas, GROOS, Stephanie, HAVERICH, Axel, MARTIN, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Applied cell therapy and gene therapy Biological and medical sciences Biotechnology Cells, Cultured Epithelial Cells - metabolism Fundamental and applied biological sciences. Psychology Gene targeting Gene therapy Genetic Vectors Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Health. Pharmaceutical industry Humans Industrial applications and implications. Economical aspects Lentivirus - genetics Medical sciences Methods Mice Phenotype Promoter Regions, Genetic Pulmonary Alveoli - cytology Pulmonary Alveoli - metabolism Pulmonary Surfactant-Associated Protein C - genetics Rats Transduction, Genetic Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transgenes
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