Activating B Cell Signaling with Defined Multivalent Ligands

Depending on the stimuli they encounter, B lymphocytes engage in signaling events that lead to immunity or tolerance. Both responses are mediated through antigen interactions with the B cell antigen receptor (BCR). Antigen valency is thought to be an important parameter in B cell signaling, but syst...

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Veröffentlicht in:	ACS chemical biology 2007-04, Vol.2 (4), p.252-262
Hauptverfasser:	Puffer, Erik B, Pontrello, Jason K, Hollenbeck, Jessica J, Kink, John A, Kiessling, Laura L
Format:	Artikel
Sprache:	eng
Schlagworte:	2,4-Dinitrophenol - chemistry 2,4-Dinitrophenol - immunology Animals B-Lymphocytes - immunology B-Lymphocytes - physiology Haptens Ligands Mice Mice, Inbred BALB C Receptors, Antigen, B-Cell - physiology Signal Transduction - drug effects
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