Bicarbonate-Induced phosphorylation of p270 protein in mouse sperm by cAMP-Dependent protein kinase

Signaling by cAMP‐dependent protein kinase (PKA) plays an important role in the regulation of mammalian sperm motility. However, it has not been determined how PKA signaling leads to changes in motility, and specific proteins responsible for these changes have not yet been identified as PKA substrat...

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Veröffentlicht in:	Molecular reproduction and development 2008-06, Vol.75 (6), p.1045-1053
Hauptverfasser:	Kaneto, Masako, Krisfalusi, Michelle, Eddy, Edward M., O'Brien, Deborah A., Miki, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	A Kinase Anchor Proteins - deficiency A Kinase Anchor Proteins - genetics AKAP Animals Bicarbonates - pharmacology Biological and medical sciences capacitation Cyclic AMP-Dependent Protein Kinases - metabolism Fundamental and applied biological sciences. Psychology Male Mammalian male genital system Mice Mice, Knockout Molecular Weight Morphology. Physiology Phosphorylation PKA Proteins - chemistry Proteins - metabolism Signal Transduction - drug effects Sperm Capacitation Sperm Motility - drug effects Sperm Motility - physiology Spermatozoa - drug effects Spermatozoa - metabolism substrate Substrate Specificity Vertebrates: reproduction
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