Multiscale and modular analysis of cardiac energy metabolism: repairing the broken interfaces of isolated system components

Computational models of large molecular systems can be assembled from modules representing biological function emerging from interactions among a small subset of molecules. Experimental information on isolated molecules can be integrated with the response of the network as a whole to estimate crucia...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2008-03, Vol.1123 (1), p.155-168
1. Verfasser:	Van Beek, Johannes H G M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Creatine - metabolism Creatine Kinase - metabolism Energy Metabolism Intracellular Membranes - metabolism Kinetics Mitochondria, Heart - metabolism Models, Cardiovascular Models, Theoretical Myocardium - metabolism Nucleotides - metabolism Oxidative Phosphorylation Reproducibility of Results
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