Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease

Alzheimer's disease is the commonest dementia. One major characteristic of its pathology is accumulation of amyloid-beta (Abeta) as insoluble deposits in brain parenchyma and in blood vessel walls [cerebral amyloid angiopathy (CAA)]. The distribution of Abeta deposits in the basement membranes...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Brain pathology (Zurich, Switzerland) Switzerland), 2008-04, Vol.18 (2), p.253-266
Hauptverfasser:	Weller, Roy O, Subash, Malavika, Preston, Stephen D, Mazanti, Ingrid, Carare, Roxana O
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer Disease - therapy Amyloid beta-Peptides - metabolism Animals Cerebral Amyloid Angiopathy - metabolism Cerebral Amyloid Angiopathy - pathology Cerebral Amyloid Angiopathy - therapy Drainage - methods Humans
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!