Chimeric foot-and-mouth disease viruses: Evaluation of their efficacy as potential marker vaccines in cattle

Summary Previous work in pigs, has demonstrated that full protection against foot-and-mouth disease (FMD) can be achieved following vaccination with chimeric foot-and-mouth disease virus (FMDV) vaccines, in which the VP1 G–H loop had been substituted with that from another serotype. If proven to be...

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Veröffentlicht in:	Vaccine 2008-04, Vol.26 (16), p.1982-1989
Hauptverfasser:	Fowler, V.L, Paton, D.J, Rieder, E, Barnett, P.V
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animal diseases Animals Antibodies, Viral - blood Antibodies, Viral - immunology Antibody Specificity Antigens Applied microbiology Biological and medical sciences Capsid Proteins - genetics Cattle Cloning Economic importance Epitopes - immunology Foot & mouth disease Foot-and-mouth disease Foot-and-Mouth Disease - blood Foot-and-Mouth Disease - immunology Foot-and-Mouth Disease - prevention & control Foot-and-mouth disease virus Foot-and-Mouth Disease Virus - genetics Foot-and-Mouth Disease Virus - immunology Fundamental and applied biological sciences. Psychology Infections Injections, Intramuscular Laboratories Marker vaccines Microbiology Neutralization Tests Protection Proteins Reassortant Viruses Vaccine Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral Vaccines - administration & dosage Viral Vaccines - immunology Viruses VP1 G–H loop
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