A role for glycosphingolipid‐enriched microdomains in platelet glycoprotein Ib‐mediated platelet activation

Background: Glycoprotein (GP) Ib, a platelet von Willebrand factor (VWF) receptor, plays a crucial role in thrombosis and hemostasis. As recent reports have suggested that GPIb partially locates in a particular region, designated as glycosphingolipid‐enriched microdomains (GEMs), we hypothesized tha...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2007-05, Vol.5 (5), p.1034-1040
Hauptverfasser:	JIN, W., INOUE, O., TAMURA, N., SUZUKI‐INOUE, K., SATOH, K., BERNDT, M. C., HANDA, M., GOTO, S., OZAKI, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Adhesion GEMs Glycosphingolipids - metabolism GPIb Humans Lyn Platelet Activation - physiology Platelet Glycoprotein GPIb-IX Complex - physiology Protein Binding Signal Transduction Src src-Family Kinases - metabolism
Online-Zugang:	Volltext
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