Temporal lobe neoplasm and seizures: how deep does the story go?

[March 2008-Cleveland Case Report]. There is a well-described association between the occurrence of developmental tumors and the presence of cortical dysplasia in the neighboring brain tissue. The main surgical approaches in the treatment of medically refractory epilepsy related to such developmenta...

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Veröffentlicht in:Epileptic disorders 2008-03, Vol.10 (1), p.56-67
Hauptverfasser: Jehi, Lara E, Lüders, Hans O, Naugle, Richard, Ruggieri, Paul, Morris, Harold, Foldvary, Nancy, Wyllie, Elaine, Kotagal, Prakash, Bingaman, Bill, Dinner, Dudley, Prayson, Richard, Diehl, Beate, Alexopoulos, Andreas, Bautista, Jocelyn, Busch, Robyn
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container_end_page 67
container_issue 1
container_start_page 56
container_title Epileptic disorders
container_volume 10
creator Jehi, Lara E
Lüders, Hans O
Naugle, Richard
Ruggieri, Paul
Morris, Harold
Foldvary, Nancy
Wyllie, Elaine
Kotagal, Prakash
Bingaman, Bill
Dinner, Dudley
Prayson, Richard
Diehl, Beate
Alexopoulos, Andreas
Bautista, Jocelyn
Busch, Robyn
description [March 2008-Cleveland Case Report]. There is a well-described association between the occurrence of developmental tumors and the presence of cortical dysplasia in the neighboring brain tissue. The main surgical approaches in the treatment of medically refractory epilepsy related to such developmental tumors include a lesionectomy versus a tailored cortical resection, often guided by an invasive evaluation. This case report describes the surgical management of a 26-year-old female with olfactory auras evolving into automotor seizures and convulsions, occurring in the context of a right temporo-parietal developmental lesion. It illustrates the pros and cons of various surgical approaches, and discusses some pathophysiological aspects of developmental tumors, dysplasia and epilepsy. [Published with video sequences].
doi_str_mv 10.1684/epd.2008.0173
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source MEDLINE; John Libbey Eurotext Journals; EZB-FREE-00999 freely available EZB journals; Wiley Online Library All Journals
subjects Adult
Amobarbital
Brain - pathology
Brain Neoplasms - pathology
Brain Neoplasms - physiopathology
Brain Neoplasms - surgery
Dominance, Cerebral
Epilepsy, Temporal Lobe - pathology
Epilepsy, Temporal Lobe - physiopathology
Female
Humans
Hypnotics and Sedatives
Magnetic Resonance Imaging
Neurosurgical Procedures
Seizures - etiology
Seizures - pathology
Seizures - physiopathology
Temporal Lobe - pathology
Treatment Outcome
title Temporal lobe neoplasm and seizures: how deep does the story go?
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