Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles

Integrin adhesion receptors transduce bidirectional signals across the plasma membrane, with the integrin transmembrane domains acting as conduits in this process. Here, we report the first high-resolution structure of an integrin transmembrane domain. To assess the influence of the membrane model s...

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Veröffentlicht in:	Biochemistry (Easton) 2008-04, Vol.47 (13), p.4008-4016
Hauptverfasser:	Lau, Tong-Lay, Partridge, Anthony W, Ginsberg, Mark H, Ulmer, Tobias S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Humans Integrin beta3 - chemistry Micelles Molecular Sequence Data Phospholipids - chemistry Protein Conformation
Online-Zugang:	Volltext
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