Progression of atherosclerosis in ApoE-deficient mice that express distinct molecular forms of TNF-alpha

TNFα (TNF) critically regulates inflammation-driven atherosclerosis. Because the transmembrane (tmTNF) and soluble (sTNF) forms of TNF possess distinct immuno-modulatory properties, we hypothesized that they might differentially regulate atherosclerosis progression. Three groups of male ApoE⁻/⁻ mice...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of pathology 2008-04, Vol.214 (5), p.574-583
Hauptverfasser:	Canault, M, Peiretti, F, Poggi, M, Mueller, C, Kopp, F, Bonardo, B, Bastelica, D, Nicolay, A, Alessi, M.C, Nalbone, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aortic Diseases - genetics Aortic Diseases - metabolism Aortic Diseases - pathology Aortic Valve - pathology Apolipoproteins E - deficiency Apoptosis atherosclerosis Atherosclerosis (general aspects, experimental research) Atherosclerosis - genetics Atherosclerosis - metabolism Atherosclerosis - pathology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cholesterol - blood Diet, Atherogenic Disease Progression Gene Expression gene targeting inflammation Inflammation Mediators - metabolism Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout mouse Mutation Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques RNA, Messenger - genetics TNF transmembrane TNF Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!