(-)-Epigallocatechin gallate induces apoptosis, via caspase activation, in osteoclasts differentiated from RAW 264.7 cells

Background and Objective: Alveolar bone resorption is a characteristic feature of periodontal diseases and involves removal of both the mineral and the organic constituents of the bone matrix, a process mainly carried out by multinucleated osteoclast cells. (‐)‐Epigallocatechin gallate, the main co...

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Veröffentlicht in:	Journal of periodontal research 2007-06, Vol.42 (3), p.212-218
Hauptverfasser:	Yun, J.-H., Kim, C.-S., Cho, K.-S., Chai, J.-K., Kim, C.-K., Choi, S.-H.
Format:	Artikel
Sprache:	eng
Schlagworte:	(-)-epigallocatechin gallate Acid Phosphatase - analysis Alveolar Process - drug effects Amino Acid Chloromethyl Ketones - pharmacology Animals apoptosis Apoptosis - physiology Biological and medical sciences Bone Resorption - drug therapy caspase Caspase Inhibitors Caspases - drug effects Caspases - metabolism Catechin - analogs & derivatives Catechin - pharmacology Cell Line Cell Survival - drug effects Dentistry DNA Fragmentation Enzyme Activation Enzyme Inhibitors - pharmacology Isoenzymes - analysis Medical sciences Mice osteoclast Osteoclasts - drug effects Osteoclasts - physiology Otorhinolaryngology. Stomatology RANK Ligand - metabolism Tartrate-Resistant Acid Phosphatase
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