Quantitative Measurement of Cyclin D1 mRNA, a Potent Diagnostic Tool to Separate Mantle Cell Lymphoma From Other B-cell Lymphoproliferative Disorders

Cyclin D1 overexpression as a result of t(11;14) is a specific marker for diagnosis of mantle cell lymphoma (MCL) and plays an important role in MCL pathogenesis. To set a highly reliable cutoff value that discriminates MCL from other B-cell lymphoproliferative disorders, we performed a retrospectiv...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diagnostic molecular pathology 2008-03, Vol.17 (1), p.39-50
Hauptverfasser:	Brizova, Helena, Kalinova, Marketa, Krskova, Lenka, Mrhalova, Marcela, Kodet, Roman
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Child Diagnosis, Differential Female Gene Expression Regulation, Neoplastic Genes, bcl-1 Humans In Situ Hybridization, Fluorescence Lymph Nodes - metabolism Lymphoma, B-Cell, Marginal Zone - diagnosis Lymphoma, B-Cell, Marginal Zone - genetics Lymphoma, B-Cell, Marginal Zone - metabolism Lymphoma, Mantle-Cell - diagnosis Lymphoma, Mantle-Cell - genetics Lymphoma, Mantle-Cell - metabolism Lymphoproliferative Disorders - diagnosis Lymphoproliferative Disorders - genetics Lymphoproliferative Disorders - metabolism Male Middle Aged Polymerase Chain Reaction RNA, Messenger - analysis RNA, Messenger - metabolism Sensitivity and Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!