Comparison of Acute Physiology and Chronic Health Evaluation (APACHE) II score with organ failure scores to predict hospital mortality

Summary This study compared the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II score with two organ failure scores in predicting hospital mortality of critically ill patients. A total of 1311 consecutive adult patients in a tertiary 22‐bed multidisciplinary intensive c...

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Veröffentlicht in:Anaesthesia 2007-05, Vol.62 (5), p.466-473
Hauptverfasser: Ho, K. M., Lee, K. Y., Williams, T., Finn, J., Knuiman, M., Webb, S. A. R.
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container_end_page 473
container_issue 5
container_start_page 466
container_title Anaesthesia
container_volume 62
creator Ho, K. M.
Lee, K. Y.
Williams, T.
Finn, J.
Knuiman, M.
Webb, S. A. R.
description Summary This study compared the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II score with two organ failure scores in predicting hospital mortality of critically ill patients. A total of 1311 consecutive adult patients in a tertiary 22‐bed multidisciplinary intensive care unit (ICU) in Western Australia were considered. The APACHE II score had a better calibration and discrimination than the Max Sequential Organ Failure Score (Max SOFA) (area under receiver operating characteristic (ROC) curve 0.858 vs 0.829), Admission SOFA (area under ROC 0.858 vs 0.791), and the first day or cumulative 5‐day Royal Perth Hospital Intensive Care Unit (RPHICU) organ failure score (area under ROC 0.858 vs 0.822 and 0.819, respectively) in predicting hospital mortality. The APACHE II score predicted hospital mortality of critically ill patients better than the SOFA and RPHICU organ failure scores in our ICU.
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subjects Adult
Aged
Anatomy & physiology
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
APACHE
Biological and medical sciences
Calibration
Comparative analysis
Critical Illness - mortality
Female
Hospital Mortality
Humans
Intensive care
Intensive Care Units
Male
Medical sciences
Middle Aged
Mortality
Multiple Organ Failure - diagnosis
Multiple Organ Failure - mortality
Predictions
Prognosis
ROC Curve
Severity of Illness Index
Standard scores
Western Australia - epidemiology
title Comparison of Acute Physiology and Chronic Health Evaluation (APACHE) II score with organ failure scores to predict hospital mortality
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