Angiogenesis and antiangiogenic therapy in hematologic malignancies

Abstract Angiogenesis, the generation of new blood capillaries from preexisting blood vessels, is tightly regulated in the adult organism. Although many of the initial studies were performed on solid tumors, increasing evidence indicates that angiogenesis also plays an important role in hematologic...

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Veröffentlicht in:	Critical reviews in oncology/hematology 2007-05, Vol.62 (2), p.105-118
Hauptverfasser:	Dong, Xunwei, Han, Zhong Chao, Yang, Renchi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Angiogenesis activator Angiogenesis inhibitor Angiogenesis Inhibitors - pharmacology Animals Antiangiogenic therapy Antineoplastic Agents - pharmacology Biological and medical sciences Hematologic and hematopoietic diseases Hematologic Neoplasms - drug therapy Hematological malignancies Hematology, Oncology and Palliative Medicine Humans Medical sciences Neovascularization, Pathologic - drug therapy Neovascularization, Pathologic - physiopathology
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