Clinical Implications and Longitudinal Alteration of Peripheral Blood Transcriptional Signals Indicative of Future Cardiac Allograft Rejection

Background We have previously demonstrated that a peripheral blood transcriptional profile using 11 distinct genes predicts onset of cardiac allograft rejection weeks to months prior to the actual event. Methods In this analysis, we ascertained the performance of this transcriptional algorithm in a...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2008-03, Vol.27 (3), p.297-301
Hauptverfasser:	Mehra, Mandeep R., MD, Kobashigawa, Jon A., MD, Deng, Mario C., MD, Fang, Kenneth C., MD, Klingler, Tod M., PhD, Lal, Preeti G., PhD, Rosenberg, Steven, PhD, Uber, Patricia A., PharmD, Starling, Randall C., MD, Murali, Srinivas, MD, Pauly, Daniel F., MD, Dedrick, Russell, PhD, Walker, Michael G., PhD, Zeevi, Adriana, PhD, Eisen, Howard J., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Bayes Theorem Biological and medical sciences Cardiology. Vascular system Case-Control Studies Cohort Studies Disease Progression Gene Expression Profiling Graft Rejection - blood Graft Rejection - etiology Graft Rejection - genetics Heart Transplantation Humans Longitudinal Studies Medical sciences Risk Factors Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Transplantation, Homologous
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