Chloroquine increases low-density lipoprotein removal from plasma in systemic lupus patients

Low-density lipoprotein (LDL) pathway in systemic lupus erythematosus (SLE) patients taking chloroquine diphosphate (CDP) was evaluated through the kinetic behavior of a radioactive cholesterol-rich nanoemulsion (LDE) that resembles the LDL lipidic structure. LDE was labeled with 14C-cholesteryl est...

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Veröffentlicht in:	Lupus 2007-01, Vol.16 (4), p.273-278
Hauptverfasser:	Sachet, J.C., Borba, E.F., Bonfá, E., Vinagre, C.G.C., Silva, V.M., Maranhão, R.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antirheumatic Agents - pharmacology Chloroquine - analogs & derivatives Chloroquine - pharmacology Cholesterol, LDL - drug effects Cholesterol, LDL - metabolism Fat Emulsions, Intravenous - metabolism Female Humans Kinetics Lipoproteins, LDL - drug effects Lipoproteins, LDL - metabolism Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - drug therapy Radioactive Tracers Receptors, LDL - metabolism
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