Behavioral and neurochemical consequences of multiple MDMA administrations in the rat: Role of individual differences in anxiety-related behavior

Using the elevated plus-maze (EPM), Wistar rats can be distinguished into high (HA) or low anxiety (LA) subjects. These differences seem to reflect traits, since HA and LA rats vary also in other anxiety-dependent tasks, neurochemical mechanisms, and psychopharmacological reactivity, including lasti...

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Veröffentlicht in:	Behavioural brain research 2008-05, Vol.189 (1), p.52-64
Hauptverfasser:	Ludwig, V., Mihov, Y., Schwarting, R.K.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Anxiety - metabolism Behavior, Animal - drug effects Behavioral psychophysiology Biological and medical sciences Dopamine - metabolism Drug Administration Schedule Ecstasy Elevated plus-maze Exploratory Behavior - drug effects Fundamental and applied biological sciences. Psychology Hallucinogens - administration & dosage Individual differences Male MDMA N-Methyl-3,4-methylenedioxyamphetamine - administration & dosage N-Methyl-3,4-methylenedioxyamphetamine - pharmacology Neostriatum - drug effects Neostriatum - metabolism Neurotransmitter Uptake Inhibitors - administration & dosage Neurotransmitter Uptake Inhibitors - pharmacology Novel-object test Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Wistar Sensitization Serotonin Serotonin - metabolism Statistics, Nonparametric
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