A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction

Multifactor dimensionality reduction (MDR) was developed as a method for detecting statistical patterns of epistasis. The overall goal of MDR is to change the representation space of the data to make interactions easier to detect. It is well known that machine learning methods may not provide robust...

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Veröffentlicht in:	Genetic epidemiology 2007-05, Vol.31 (4), p.306-315
Hauptverfasser:	Velez, Digna R., White, Bill C., Motsinger, Alison A., Bush, William S., Ritchie, Marylyn D., Williams, Scott M., Moore, Jason H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Epistasis, Genetic Gene Frequency Humans Models, Genetic Polymorphism, Single Nucleotide Sample Size Software
Online-Zugang:	Volltext
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