Proteomic analysis of waldenstrom macroglobulinemia

To better understand the molecular changes that occur in Waldenstrom macroglobulinemia (WM), we employed antibody-based protein microarrays to compare patterns of protein expression between untreated WM and normal bone marrow controls. Protein expression was defined as a >2-fold or 1.3-fold chang...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2007-04, Vol.67 (8), p.3777-3784
Hauptverfasser:	HATJIHARISSI, Evdoxia, HAI NGO, ZEISMER, Steven, CABANELA, Miguel, NEHME, Alex, XIAOYING JIA, MOREAU, Anne Sophie, TREON, Steven P, FONSECA, Rafael, GERTZ, Morie A, ANDERSON, Kenneth C, WITZIG, Thomas E, LEONTOVICH, Alexey A, GHOBRIAL, Irene M, LEIEU, Xavier, TIMM, Michael, MELHEM, Mona, GEORGE, Diane, GANWEI LU, GHOBRIAL, Joanna, ALSAYED, Yazan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Apoptosis - physiology Benzoquinones - pharmacology Biological and medical sciences Bone Marrow Cells - metabolism Cell Growth Processes - physiology Female Hematologic and hematopoietic diseases Histone Deacetylase Inhibitors HSP90 Heat-Shock Proteins - antagonists & inhibitors Humans Hydroxamic Acids - pharmacology Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunopathology Lactams, Macrocyclic - pharmacology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocytes - metabolism Male Medical sciences Middle Aged Pharmacology. Drug treatments Plasma Cells - metabolism Proteomics Reproducibility of Results Tumors Waldenstrom Macroglobulinemia - metabolism Waldenstrom Macroglobulinemia - pathology
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