Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics

Objectives Triclosan is in widespread use in domestic, commercial and healthcare settings and is used to reduce methicillin-resistant Staphylococcus aureus (MRSA) load in carriers. Triclosan resistance is uncommon, usually being due to mutation in fabI or overexpression of efflux pumps. This study i...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2007-05, Vol.59 (5), p.848-853
Hauptverfasser:	Bayston, Roger, Ashraf, Waheed, Smith, Toni
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents, Local - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents antimicrobial biomaterials Bacteria Bacterial diseases Biological and medical sciences Chemicals Disk Diffusion Antimicrobial Tests Drug resistance Drug Resistance, Bacterial Human bacterial diseases Humans Infectious diseases Luminescent Measurements Medical sciences Methicillin Resistance Microbial Viability - drug effects MRSA Pharmacology. Drug treatments SCV Silicones Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Staphylococcus aureus - cytology Staphylococcus aureus - drug effects Staphylococcus aureus - isolation & purification Staphylococcus infections Triclosan - pharmacology
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