Instabilities in multiserotype disease models with antibody-dependent enhancement

This paper investigates the complex dynamics induced by antibody-dependent enhancement (ADE) in multiserotype disease models. ADE is the increase in viral growth rate in the presence of immunity due to a previous infection of a different serotype. The increased viral growth rate is thought to increa...

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Veröffentlicht in:	Journal of theoretical biology 2007-05, Vol.246 (1), p.18-27
Hauptverfasser:	Billings, Lora, Schwartz, Ira B., Shaw, Leah B., McCrary, Marie, Burke, Donald S., Cummings, Derek A.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - immunology Antibody-Dependent Enhancement Dengue Disease Outbreaks Epidemics Humans Models, Immunological Multiserotype Nonlinear Dynamics Vaccination Vaccine Virulence Virus Diseases - immunology Virus Diseases - prevention & control Viruses - immunology
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