Axin bridges Daxx to p53

The death domain-associated protein Daxx exerts many reported functions that include mediating the signaling from FasL to apoptosis via activating the c-Jun N-terminal kinase (JNK), induction and inhibition of apoptosis, and regulation of chromatin remodeling. It was originally cloned from a yeast t...

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Veröffentlicht in:	Cell research 2007-04, Vol.17 (4), p.301-302
Hauptverfasser:	Lin, Sheng-Cai, Li, Qinxi
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Adaptor Proteins, Signal Transducing - physiology Animals Apoptosis Axin Protein Biomedical and Life Sciences Carrier Proteins - genetics Carrier Proteins - physiology Cell Biology Cell Nucleus - metabolism commentary Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - physiology Life Sciences Mice Mice, Knockout Nuclear Proteins - genetics Nuclear Proteins - physiology Phosphorylation Protein Binding Protein-Serine-Threonine Kinases - physiology Repressor Proteins - physiology Signal Transduction Tumor Suppressor Protein p53 - physiology
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