A Gata2 intronic enhancer confers its pan-endothelia-specific regulation

GATA-2, a transcription factor that has been shown to play important roles in multiple organ systems during embryogenesis, has been ascribed the property of regulating the expression of numerous endothelium-specific genes. However, the transcriptional regulatory hierarchy governing Gata2 activation...

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Veröffentlicht in:	Development (Cambridge) 2007-05, Vol.134 (9), p.1703-1712
Hauptverfasser:	Khandekar, Melin, Brandt, William, Zhou, Yinghui, Dagenais, Susan, Glover, Thomas W, Suzuki, Norio, Shimizu, Ritsuko, Yamamoto, Masayuki, Lim, Kim-Chew, Engel, James Douglas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Chromosomes, Artificial, Yeast Endothelium - metabolism Enhancer Elements, Genetic GATA2 Transcription Factor - metabolism Gene Expression Regulation Introns Mice Mice, Inbred Strains Mice, Transgenic Molecular Sequence Data
Online-Zugang:	Volltext
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